Volume 19, Number 8—August 2013
Dispatch
Recombinant Coxsackievirus A2 and Deaths of Children, Hong Kong, 2012
Table
Pairwise sequence identities between coxsackievirus A2 strains from 4 children Hong Kong, China, 2012, in and other representative human enterovirus A strains
Region | Nucleotide identity, % |
Amino acid identity, % |
|||
---|---|---|---|---|---|
CVA2F | Other human enterovirus A strains | CVA2F | Other human enterovirus A strains | ||
5′-UTR |
84.9–85.3 |
71.1–87.2 |
NA |
NA |
|
Polyprotein |
79.3–79.4 |
69.1–78.4 |
96–96.1 |
76–88.4 |
|
P1 | 81.6–81.7 | 64.8–69.1 | 96.9–97 | 67.4–74.6 | |
VP4 | 80.2–80.7 | 61.8–70.8 | 97.1 | 63.8–81.2 | |
VP2 | 81.6 | 66.1–70.3 | 97.6 | 72.9–79.2 | |
VP3 | 82.4–82.6 | 66.1–72.8 | 97.1–97.5 | 70.7–83.3 | |
VP1 |
81.1–81.2 |
60.1–65.9 |
95.9–96.3 |
56.7–67.3 |
|
P2 | 78–78.2 | 70.5–83.8 | 96.9–97.1 | 78.9–98.4 | |
2A | 78–78.2 | 65.3–82 | 96 | 69.3–98.7 | |
2B | 73.7–74.1 | 66–84.2 | 94.9 | 76.8–99 | |
2C |
79.2–79.4 |
71.9–86.3 |
97.9–98.2 |
83–98.8 |
|
P3 | 77.8–77.9 | 72–87.8 | 94.4–94.6 | 81.1–97.9 | |
3A | 79.8–80.6 | 69–86.4 | 94.2–95.3 | 68.6–98.8 | |
3B | 74.2 | 62.1–93.9 | 90.9 | 68.2–95.5 | |
3C | 77.4 | 72.3–87.4 | 95.1 | 84.2–98.9 | |
3D |
77.7–77.9 |
72.2–89.6 |
94.2–94.4 |
82.7–98.5 |
|
3′-UTR | 83.3–84.5 | 38.9–96.3 | NA | NA |
*CVA2F, coxsackievirus A prototype strain Fleetwood; UTR, untranslated region; NA, not applicable; P1, capsid protein 1; VP, viral protein; P2, nonstructural protein 2; P3, nonstructural protein 3.