Volume 19, Number 9—September 2013
Macrolide-Resistant Mycoplasma pneumoniae in Humans, Ontario, Canada, 2010–2011
|P1 gene type||No. isolates||Variant||Reference||GenBank accession no.†||Nucleotide homology, %||Amino acid homology, %||Nonsynonymous mutations compared with reference (no. isolates)||No. VTR AGT sequences||No. drug-resistant isolates|
|1||16||NA||M129||U00089.2||99.7–99.9||99.5–99.9||E179K (7), D559N (1), Q1232E (4)||7–11||3|
|2||8||NA||Mp1842||AF290002.1||99.6–99.9||99.5–99.8||S841L, E962D, I1302V||7–11||1|
|3||2a||Mpn309||AP012303.1||99.8–99.9||99.5–99.6||Y210N (1), T837N (3)||6||0|
|8||2b||T-103||AB691539.1||99.5–99.9||99.5–99.9||S1516P: 6 isolates had a deletion at 1244-QTNS-1247||7–9||1|
*VTR, variable tandem repeat. NA, not applicable (strains M129 and Mp1842 are considered prototypes representative for types 1 and 2).
†The sequences of the P1 gene generated in this study have been deposited in GenBank (accession nos. KF154740–KF154759).