TY - JOUR AU - Douet, Jean Yves AU - Zafar, Saima AU - Perret-Liaudet, Armand AU - Lacroux, Caroline AU - Lugan, Séverine AU - Aron, Naima AU - Cassard, Herve AU - Ponto, Claudia AU - Corbière, Fabien AU - Torres, Juan Maria AU - Zerr, Inga AU - Andreoletti, Olivier T1 - Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease T2 - Emerging Infectious Disease journal PY - 2014 VL - 20 IS - 1 SP - 114 SN - 1080-6059 AB - We report the presence of infectivity in erythrocytes, leukocytes, and plasma of 1 person with variant Creutzfeldt-Jakob disease and in the plasma of 2 in 4 persons whose tests were positive for sporadic Creutzfeldt-Jakob disease. The measured infectivity levels were comparable to those reported in various animals with transmissible spongiform encephalopathies. KW - Creutzfeldt-Jakob KW - vCJD KW - sCJD KW - prion KW - blood KW - infectivity KW - spongiform KW - Creutzfeldt-Jakob disease KW - CJD KW - prions KW - transmissible spongiform encephalopathy KW - TSE DO - 10.3201/eid2001.130353 UR - https://wwwnc.cdc.gov/eid/article/20/1/13-0353_article ER - End of Reference