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Volume 20, Number 11—November 2014
Letter

Evidence of Evolving Extraintestinal Enteroaggregative Escherichia coli ST38 Clone

Marie Anne ChattawayComments to Author , Claire Jenkins, Holly Ciesielczuk, Martin Day, Vivienne DoNascimento, Michaela Day, Irene Rodríguez, Alieda van Essen-Zandbergen, Anne-Kathrin Schink, Guanghui Wu, John Threlfall, Martin J. Woodward, Nick Coldham, Kristina Kadlec, Stefan Schwarz, Cindy M. Dierikx, Beatriz Guerra, Reiner Helmuth, Dik J. Mevius, Neil Woodford, John Wain, on behalf of the SAFEFOODERA
Author affiliations: Public Health England, Colindale, London, UK (M.A. Chattaway, C. Jenkins, H. Ciesielczuk, Martin Day, V. DoNascimento, Michaela Day, J. Threlfall, N. Woodford, J. Wain); Hospital Universitario Ramón y Cajal, Madrid, Spain (I. Rodríguez); University of East Anglia, Norfolk, UK (J. Wain); Federal Institute for Risk Assessment, Berlin, Germany (I. Rodríguez, B. Guerra, R. Helmuth); Central Veterinary Institute of Wageningen, Lelystad, the Netherlands (A. van Essen-Zandbergen, C. Dierikx, D. Mevius); Friedrich-Loeffler-Institut, Neustadt-Mariensee, Germany (A.-K. Schink, K. Kadlec, S. Schwarz); Animal Health and Veterinary Laboratories Agency, Weybridge, UK (G. Wu, M.J. Woodward, N. Coldham)

Main Article

Table

Characteristics of human-derived ESBL-producing enteroaggregative Escherichia coli isolates from sources in Germany, the Netherlands, and the United Kingdom*

Isolate Serotype† ST Cplx‡ Country Source Phylotype aggR§ Plasmidic ESBL
ESBL-723 OR:H30 38 38 UK Urine D + CTX-M-15
ESBL-746 O125ac:H30 38 38 UK Urine D + CTX-M-15
ESBL-884 O19a:H30 38 38 UK Urine D + CTX-M-14
ESBL-831 O19a:H30 38 38 UK Urine D + CTX-M-14
ESBL-815 O19a:H30 38 38 UK Blood D + CTX-M-15
ESBL-26 O153:H30 38 38 Netherlands Urine D + CTX-M-51
ESBL-221 O92:H33 34 10 Germany Feces A + CTX-M-3
ESBL-45 O?:H26 58 155 Netherlands Urine B1 +/− CTX-M-14
ESBL-46 O?:H- 694 None Netherlands Urine A +/− CTX-M-15
ESBL-48 O15:H1 545 None Netherlands Urine D +/− CTX-M-1
ESBL-64 O?:H23 224 None Netherlands Urine B1 +/− CTX-M-1

*All isolates were collected in 2009 (4). ESBL, extended-spectrum β-lactamase. ST, sequence type.
†H- not motile; O?, O unidentifiable; R, rough reaction.
‡Cplx–ST complex comprising single-locus variants.
§aggR, enteroaggregative E. coli regulatory gene; +, positive in screen and isolates; −, negative in screen and isolates; +/−, positive in screen but negative in isolates, indicating unstable plasmid.

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References
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