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Volume 20, Number 2—February 2014

Crimean-Congo Hemorrhagic Fever Virus, Greece

Anna PapaComments to Author , Persefoni Sidira, Victor Larichev, Ludmila Gavrilova, Ksenia Kuzmina, Mehrdad Mousavi-Jazi, Ali Mirazimi, Ute Ströher, and Stuart Nichol
Author affiliations: Aristotle University of Thessaloniki School of Medicine, Thessaloniki, Greece (A. Papa, P. Sidira); D.I. Ivanovsky Institute of Virology, Moscow, Russian Federation (V. Larichev, L. Gavrilova, K. Kuzmina); Swedish Institute for Communicable Disease Control, Stockholm, Sweden (M. Mousavi-Jazi, A. Mirazimi); National Veterinary Institute, Uppsala, Sweden (A. Mirazimi); Linköpings University Institute of Clinical and Experimental Medicine, Linköping, Sweden (A. Mirazimi); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (U. Ströher, S. Nichol)

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Results of ELISA and IFA testing of 118 serum samples initially positive for CCHFV by ELISA, Greece*

Result No. (%) samples
Initial ELISA† CDC ELISA‡ Ivanovsky Institute ELISA§ IFA¶
High-positive 76 (64.4) 61 (51.7) 73 (61.8) 78 (66.1)
Positive 29 (24.6) 43 (36.4) 30 (25.4) 26 (22.0)
Low-positive 13 (11.0) 13 (11.0) 13 (11.0) 13 (11.0)
Negative NA 1 (0.8) 2 (1.7) 1 (0.8)

*IFA, immunofluorescence assay; CCHFV, Crimean-Congo hemorrhagic fever virus; CDC, US Centers for Disease Control and Prevention; NA, not applicable.
†Samples were initially collected and tested for IgG by ELISA (Vektor-Best, Novosibirsk, Russia) as part of 3 previous seroprevalence studies (911).
‡CDC, Atlanta, Georgia, USA (13).
§Ivanovsky Institute of Virology, Moscow, Russia (12).
¶CCHFV Mosaic 2; Euroimmun Medizinische Labordiagnostika AG, Lübeck, Germany.

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Page created: January 17, 2014
Page updated: January 17, 2014
Page reviewed: January 17, 2014
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