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Volume 20, Number 2—February 2014

NDM-1–producing Strains, Family Enterobacteriaceae, in Hospital, Beijing, China

Guang Zhou1, Si Guo1, Yanping Luo, Liyan Ye, Yang Song, Guangwei Sun, Ling Guo, Yong Chen, Li Han, and Jiyong YangComments to Author 
Author affiliations: Chinese PLA General Hospital, Beijing, China (G. Zhou, Y. Luo, L. Ye, Y. Song, G. Sun, L. Guo, J. Yang); Henan Provincial People’s Hospital, Zhengzhou, China (S. Guo); Chinese PLA Institute for Disease Control and Prevention, Academy of Military Medical Sciences, Beijing (Y. Chen, L. Han)

Main Article


Phenotype and molecular characteristics of NDM-1–producing strains isolated from Chinese PLA General Hospital, Beijing, China, 2009–2013*

Isolate no. Organism Source ST† Size, type of blaNDM-1 plasmid Prevalence of RDs MICs, mg/L
IR5028 Escherichia coli Urine 167 ≈190 kb, A/C blaTEM, blaOXA-1,‡ blaCTX-group 1, 2, 9, aac(6′)-Ib-crarmA >256 >256 >256 >32 >32 >32 >256 >32.0
IR5047 Klebsiella pneumoniae Blood 1,240 ≈50 kb, X3 blaTEM, blaSHV, blaOXA-1, qnrS,‡oqxAB >256 64 >256 8 6 >32 2 0.38
IR5337 Providencia rettgeri Urine NA‡ ≈190 kb, A/C blaPER, blaCMY, mtC >256 >256 >256 >32 >32 4 >256 >32.0
IR5338 Enterobacter cloacae Urine NA ≈50 kb, X3 blaSHV,‡ blaOXA-1,blaCTX-group 2 >256 >256 >256 >32 >32 >32 1.5 2.0
IR5343 Raoultella ornithinolytica Abscess NA ≈70 kb, N qnrS >256 32 >256 >32 >32 >32 2 0.75

*NDM-1, New Delhi metallo-β-lactamase-1–producing; ST, sequence type; RDs, resistance determinants; CTX, cefotaxime; FEP: cefepime; TZP, piperacillin-tazobactam; IMP, imipenem; MEM, meropenem; ETP, ertapenem; AK, amikacin; LVX, levofloxacin; NA, not applicable.
†The alleles at each of the multi-locus ST loci for a given isolate are combined into an allelic profile and assigned an ST designation.
‡Shown to be transferred by conjugation experiments.

Main Article

1These authors contributed equally to this work.

Page created: January 08, 2014
Page updated: January 08, 2014
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