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Volume 20, Number 3—March 2014

Concomitant Multidrug-resistant Pulmonary Tuberculosis and Susceptible Tuberculous Meningitis

Christine BernardComments to Author , Florence Brossier, Mathilde Fréchet-Jachym, Philippe C. Morand, Sophie Coignard, Elisabeth Aslangul, Alexandra Aubry, Vincent Jarlier, Wladimir Sougakoff, and Nicolas Veziris
Author affiliations: Université Pierre et Marie Curie, Paris, France (C. Bernard, F. Brossier, A. Aubry, V. Jarlier, W. Sougakoff, N. Veziris); Hôpital Pitié-Salpêtrière, Paris (C. Bernard, F. Brossier, A. Aubry, V. Jarlier, W. Sougakoff, N. Veziris); Centre Médical de Bligny, Briis sous Forges, France (M. Fréchet-Jachym); Groupe Hospitalier Cochin, Paris (P. C. Morand, S. Coignard); Université Paris Descartes, Paris (P. C. Morand); Hôpital Hôtel-Dieu, Paris (E. Aslangul)

Main Article


Localization, drug-susceptibility results, and MIRU-VNTR genotypes of Mycobacterium tuberculosis strains recovered from a man with both pulmonary tuberculosis and tuberculous meningitis, France, 2012*

Tissue MIRU-VNTR genotype 1 222213222234225153333622 MIRU-VNTR genotype 2 224243122234225143335622
Lung Isoniazid and rifampin resistant, fluoroquinolone susceptible, rpoB S531L, katG S315T, no mutations in gyrA and gyrB Pan-susceptible except to fluoroquinolones, no mutations in rpoB, katG, and gyrA; gyrB N538D
Cerebrospinal fluid

Pan-susceptible, no mutations in rpoB, katG, gyrA, and gyrB
*MIRU-VNTR, mycobacterial interspersed repetitive unit–variable number tandem repeat.

Main Article

Page created: February 20, 2014
Page updated: February 20, 2014
Page reviewed: February 20, 2014
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