TY - JOUR AU - Page, Anne-Laure AU - Jusot, Viviane AU - Mamaty, Abdoul-Aziz AU - Adamou, Lagare AU - Kaplon, Jérôme AU - Pothier, Pierre AU - Djibo, Ali AU - Manzo, Mahamane AU - Toure, Brahima AU - Langendorf, Céline AU - Collard, Jean-Marc AU - Grais, Rebecca T1 - Rotavirus Surveillance in Urban and Rural Areas of Niger, April 2010–March 2012 T2 - Emerging Infectious Disease journal PY - 2014 VL - 20 IS - 4 SP - 573 SN - 1080-6059 AB - Knowledge of rotavirus epidemiology is necessary to make informed decisions about vaccine introduction and to evaluate vaccine impact. During April 2010–March 2012, rotavirus surveillance was conducted among 9,745 children <5 years of age in 14 hospitals/health centers in Niger, where rotavirus vaccine has not been introduced. Study participants had acute watery diarrhea and moderate to severe dehydration, and 20% of the children were enrolled in a nutrition program. Of the 9,745 children, 30.6% were rotavirus positive. Genotyping of a subset of positive samples showed a variety of genotypes during the first year, although G2P[4] predominated. G12 genotypes, including G12P[8], which has emerged as a predominant strain in western Africa, represented >80% of isolates during the second year. Hospitalization and death rates and severe dehydration among rotavirus case-patients did not differ during the 2 years. The emergence of G12P[8] warrants close attention to the characteristics of associated epidemics and possible prevention measures. KW - rotavirus KW - genotyping KW - diarrheal diseases KW - Niger KW - developing countries KW - malnutrition KW - Africa KW - rotavirus strain G12P[8] KW - surveillance KW - gastroenteritis KW - viruses DO - 10.3201/eid2004.131328 UR - https://wwwnc.cdc.gov/eid/article/20/4/13-1328_article ER - End of Reference