TY - JOUR AU - Parra, Gabriel AU - Green, Kim T1 - Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes T2 - Emerging Infectious Disease journal PY - 2014 VL - 20 IS - 6 SP - 1016 SN - 1080-6059 AB - We investigated sequential episodes of acute norovirus gastroenteritis in a young child within an 11-month period. The infections were caused by 2 distinct genotypes (GII.4 and GII.6). Failure to achieve cross-protective immunity was linked to absence of an enduring and cross-reactive mucosal immune response, a critical consideration for vaccine design. KW - Norovirus KW - diarrhea KW - immunity KW - genotype KW - viruses DO - 10.3201/eid2006.131627 UR - https://wwwnc.cdc.gov/eid/article/20/6/13-1627_article ER - End of Reference