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Volume 20, Number 6—June 2014
Dispatch

New Hepatitis E Virus Genotype in Camels, the Middle East

Patrick C.Y. Woo1Comments to Author , Susanna K.P. Lau1, Jade L.L. Teng1, Alan K. L. Tsang1, Marina Joseph, Emily Y.M. Wong, Ying Tang, Saritha Sivakumar, Jun Xie, Ru Bai, Renate Wernery, Ulrich Wernery, and Kwok-Yung Yuen
Author affiliations: State Key Laboratory of Emerging Infectious Diseases, Hong Kong, China (P.C.Y. Woo, S.K.P. Lau, K.-Y. Yuen); The University of Hong Kong, Hong Kong (P.C.Y. Woo, S.K.P. Lau, J.L.L. Teng, A.K.L. Tsang, E.Y.M. Wong, Y. Tang, J. Xie, R. Bai, K.-Y. Yuen); Central Veterinary Research Laboratory, Dubai, United Arab Emirates (M. Joseph, S. Sivakumar, R. Wernery, U. Wernery)

Main Article

Figure 2

Phylogenetic analyses of open reading frame (ORF) 1 (A), ORF2 (B), ORF3 (C), and ORF1/ORF2 proteins, excluding the hypervariable region (HVR) (D) of hepatitis E virus (HEV) from dromedary camels (DcHEV). The trees were constructed by using Bayesian methods of phylogenetic reconstruction (www.fifthdimension.jp/products/mrbayes5d/), and ProtTest-suggested JTT+I+G+F, MtMam+I+G+F, HIVw+I+G+F, and JTT+I+G+F (http://darwin.uvigo.es/software/prottest.html) are the optimal substitution models for ORF1,

Figure 2. Phylogenetic analyses of open reading frame (ORF) 1 (A), ORF2 (B), ORF3 (C), and ORF1/ORF2 proteins, excluding the hypervariable region (HVR) (D) of hepatitis E virus (HEV) from dromedary camels (DcHEV)The trees were constructed by using Bayesian methods of phylogenetic reconstruction (www.fifthdimension.jp/products/mrbayes5d/), and ProtTest-suggested JTT+I+G+F, MtMam+I+G+F, HIVw+I+G+F, and JTT+I+G+F (http://darwin.uvigo.es/software/prottest.html) are the optimal substitution models for ORF1, ORF2, ORF3, and concatenated ORF1/ORF2 excluding HVR, respectivelyFor this analysis we included amino acid positions 1698, 660, 113, and 2282 in ORF1, ORF2, ORF3 and concatenated ORF1/ORF2 excluding HVR, respectivelyFor ORF2 and concatenated ORF1/ORF2 excluding HVR, the scale bars indicate the estimated number of substitutions per 50 aaFor ORF1 and ORF3, the scale bars indicate the estimated number of substitutions per 20 aaBoldface indicates the 2 strains of DcHEV with complete genomes sequenced in this study.

Main Article

1These authors contributed equally to this article.

Page created: May 16, 2014
Page updated: May 16, 2014
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