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Volume 20, Number 7—July 2014
Research

Borrelia miyamotoi sensu lato Seroreactivity and Seroprevalence in the Northeastern United States

Peter J. KrauseComments to Author , Sukanya Narasimhan, Gary P. Wormser, Alan G. Barbour, Alexander E. Platonov, Janna Brancato, Timothy Lepore, Kenneth Dardick, Mark Mamula, Lindsay Rollend, Tanner K. Steeves, Maria Diuk-Wasser, Sahar Usmani-Brown, Phillip Williamson, Denis S. Sarksyan, Erol Fikrig, Durland Fish, and the Tick Borne Diseases Group
Author affiliations: Yale School of Public Health, New Haven, Connecticut, USA (P.J. Krause, J. Brancato, L. Rollend, T.K. Steeves, M. Diuk-Wasser, D. Fish); Yale School of Medicine, New Haven (P.J. Krause, S. Narasimhan, M. Mamula, E. Fikrig); New York Medical College, Valhalla, New York, USA (G.P. Wormser); University of California, Irvine, California, USA (A.G. Barbour); Central Research Institute of Epidemiology, Moscow, Russia (A.E. Platonov); Nantucket Cottage Hospital, Nantucket, Massachusetts, USA (T. Lepore); Mansfield Family Practice, Mansfield, Connecticut, USA (K. Dardick); L2 Diagnostics, LLC, New Haven (S. Usmani-Brown); Creative Testing Solutions, Tempe, Arizona, USA (P. Williamson); State Medical Academy, Izhevsk, Russia (D.S. Sarksyan)

Main Article

Table 1

Assay results for patient samples seroreactive to Borrelia miyamotoi sensu lato antigen, northeastern United States, 1991�?"2012

Group no, description, participant no. Year sample obtained IgG ELISA Western blot IgM Western blot IgG
Group 1, healthy participants (n = 639)
1 1995 1:320 Positive Positive
2 2000 >1:1280 Negative Positive
3 1991 >1:1280 Positive Positive
4 1993 >1:1280 Negative Positive
5 2000 >1:1280 Negative Positive
6 2000 >1:1280 Negative Positive
7 2012 >1:1280 Negative Positive
8 2012 >1:1280 Negative Positive
9 2012 >1:1280 Negative Positive
10 2012 >1:1280 Negative Positive
11 1993 >1:1280 Negative Positive
12 1993 1:320 Negative Positive
13 2012 1:320 Negative Positive
14 2012 >1:1280 Positive Positive
15 2012 1:640 Negative Positive
16 2002 >1:1280 Negative Positive
17 2002 >1:1280 Negative Positive
18 2002 >1:1280 Negative Positive
19 2002 >1:1280 Negative Positive
20 2000 >1:1280 Negative Positive
21 2000 >1:1280 Negative Positive
22 2002 >1:1280 Negative Positive
23 2002 >1:1280 Negative Positive
24 2002 >1:1280 Positive Positive
25
 2002
 >1:1280
 Positive
 Positive
Group 2, adults with Lyme disease (n = 194)
26
Acute-phase serum 1992 Jul 17 1:80 (negative) Negative Negative
Convalescent-phase serum 1992 Jul 27 1:1280 Negative Positive
27
Acute-phase serum 1997 Jul 27 1:160 (negative) Negative Negative
Convalescent-phase serum 1997 Aug 26 1:1280 Positive Positive
28
Acute-phase serum 1996 Jun 30 1:80 (negative) Positive Positive
Convalescent-phase serum 1996 Jul 10 1:320 Negative Positive
29
Acute-phase serum 1997 Aug 7 1:80 (negative) Negative Negative
Convalescent-phase serum 1997 Aug 17 >1:1280 Negative Positive
30 1995 >1:1280 Negative Positive
31 1991 >1:1280 Positive Positive
32 2004 1:640 Negative Positive
33 2004 1:320 Positive Positive
34 2000 >1:1280 Negative Positive
35 2011 >1:1280 Negative Positive
36 1995 >1:1280 Negative Positive
37 1994 >1:1280 Negative Positive
38 1998 1:320 Positive Positive
39 2000 >1:1280 Negative Positive
40 1998 >1:1280 Positive Positive
41 2006 >1:1280 Negative Positive
42 2002 >1:1280 Negative Positive
43 2002 1:320 Negative Positive
44
 1995
 1:320
 Positive
 Positive
Group 3, adults with virus-like illness (n = 221)
45
Acute-phase serum 1996 Jul 8 1:80 (negative) Positive Negative
Convalescent-phase serum 1996 Jul 19 1:320 Positive Positive
46 2011 >1:1280 Positive Positive
47 1997 >1:1280 Negative Positive
48 1991 >1:1280 Negative Positive
49 1991 >1:1280 Negative Positive
50 1993 >1:1280 Negative Positive
51 1997 1:320 Negative Positive
52 1992 1:320 Negative Positive

Main Article

1Members of the Tick Borne Diseases Group are listed at the end of this article.

Page created: May 06, 2014
Page updated: May 06, 2014
Page reviewed: May 06, 2014
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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