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Volume 20, Number 7—July 2014

Diphtheria-like Disease Caused by Toxigenic Corynebacterium ulcerans Strain

Vartul Sangal, Leena Nieminen, Barbara Weinhardt, Jane Raeside, Nicholas P. Tucker, Catalina-Diana Florea, Kevin G. Pollock, and Paul A. HoskissonComments to Author 
Author affiliations: Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland, UK (V. Sangal, L. Nieminen, N.P. Tucker, P.A. Hoskisson); Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne, UK (V. Sangal); Health Protection Scotland, Glasgow (K.G. Pollock); Royal Alexandra Hospital, Paisley, UK (B. Weinhardt, J. Raeside, C.-D. Florea)

Main Article


Virulence genes associated with Corynebacterium ulcerans present in strain RAH1 isolated from patient with diphtheria-like disease, 2013, United Kingdom*

Gene Strains Strain RAH1 Potential function
tox 0102 P Diphtheria-like toxin
rbp 809 A Shiga toxin–like ribosome binding protein
cpp 809, BR-AD22, 0102 P Corynebacterial protease CP40, protective antigen against caseous lymphadenitis
pld 809, BR-AD22, 0102 P Toxic phospholipase D
spaF 809, BR-AD22, 0102 P Surface-anchored protein, pilus tip protein
spaE 809, BR-AD22, 0102 P Surface-anchored protein, minor pilin subunit
spaD 809, BR-AD22, 0102 P Surface-anchored protein, major pilin subunit
spaC 809, BR-AD22, 0102 P† Surface-anchored protein, pilus tip protein
spaB 809, BR-AD22, 0102 P Surface-anchored protein, minor pilin subunit
rpfI 809, BR-AD22, 0102 P Resuscitation-promoting factor interacting protein
cwlH 809, BR-AD22, 0102 P Cell wall–associated hydrolase
nanH 809, BR-AD22, 0102 P Neuraminidase, glycosyl hydrolases
vsp1 809, BR-AD22 P Venom serine protease
vsp2 809 P Venom serine protease
tspA 809, BR-AD22 P Trypsin-like serine protease

*P, present; A, absent.
†≈700 bp deletion.

Main Article

Page created: June 18, 2014
Page updated: June 18, 2014
Page reviewed: June 18, 2014
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