TY - JOUR AU - Zhang, Hai-Lin AU - Zhang, Yu-Zhen AU - Yang, Wei-Hong AU - Tao, Xiao-Yan AU - Li, Hao AU - Ding, Ji-Chao AU - Feng, Yun AU - Yang, Du-Juan AU - Zhang, Juan AU - He, Jiang AU - Shen, Xin-Xin AU - Wang, Li-Hua AU - Zhang, Yun-Zhi AU - Song, Miao AU - Tang, Qing T1 - Molecular Epidemiology of Reemergent Rabies in Yunnan Province, Southwestern China T2 - Emerging Infectious Disease journal PY - 2014 VL - 20 IS - 9 SP - 1433 SN - 1080-6059 AB - Yunnan Province in China borders 3 countries (Vietnam, Laos, and Myanmar) in Southeast Asia. In the 1980s, a large-scale rabies epidemic occurred in this province, which subsided by the late 1990s. However, 3 human cases of rabies in 2000 indicated reemergence of the disease in 1 county. In 2012, rabies was detected in 77 counties; 663 persons died of rabies during this new epidemic. Fifty two rabies virus strains obtained during 2008–2012 were identified and analyzed phylogenetically by sequencing the nucleoprotein gene. Of the 4 clades identified, clades YN-A and YN-C were closely related to strains from neighboring provinces, and clade YN-B was closely related to strains from Southeast Asia, but formed a distinct branch. Rabies virus diversity might be attributed to dog movements among counties, provinces, and neighboring countries. These findings suggest that Yunnan Province is a focal point for spread of rabies between Southeast Asia and China. KW - rabies KW - rabies virus KW - viruses KW - molecular epidemiology KW - endemic disease KW - public health KW - nucleoprotein KW - homology KW - phylogenetic analysis KW - China KW - dogs DO - 10.3201/eid2009.130440 UR - https://wwwnc.cdc.gov/eid/article/20/9/13-0440_article ER - End of Reference