TY - JOUR AU - Bowman, Andrew AU - Nelson, Sarah AU - Page, Shannon AU - Nolting, Jacqueline AU - Killian, Mary AU - Sreevatsan, Srinand AU - Slemons, Richard T1 - Swine-to-Human Transmission of Influenza A(H3N2) Virus at Agricultural Fairs, Ohio, USA, 2012 T2 - Emerging Infectious Disease journal PY - 2014 VL - 20 IS - 9 SP - 1472 SN - 1080-6059 AB - Agricultural fairs provide an opportunity for bidirectional transmission of influenza A viruses. We sought to determine influenza A virus activity among swine at fairs in the United States. As part of an ongoing active influenza A virus surveillance project, nasal swab samples were collected from exhibition swine at 40 selected Ohio agricultural fairs during 2012. Influenza A(H3N2) virus was isolated from swine at 10 of the fairs. According to a concurrent public health investigation, 7 of the 10 fairs were epidemiologically linked to confirmed human infections with influenza A(H3N2) variant virus. Comparison of genome sequences of the subtype H3N2 isolates recovered from humans and swine from each fair revealed nucleotide identities of >99.7%, confirming zoonotic transmission between swine and humans. All influenza A(H3N2) viruses isolated in this study, regardless of host species or fair, were >99.5% identical, indicating that 1 virus strain was widely circulating among exhibition swine in Ohio during 2012. KW - Influenza A virus KW - swine KW - public health KW - livestock KW - exhibits KW - zoonotic infections KW - zoonoses KW - H3N2v KW - viruses KW - Ohio KW - fairs KW - USA DO - 10.3201/eid2009.131082 UR - https://wwwnc.cdc.gov/eid/article/20/9/13-1082_article ER - End of Reference