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Volume 21, Number 12—December 2015
Letter

Severe Ocular Cowpox in a Human, Finland

Paula M. KinnunenComments to Author , Juha M. Holopainen, Heidi Hemmilä, Heli Piiparinen, Tarja Sironen, Tero Kivelä, Jenni Virtanen, Jukka Niemimaa, Simo Nikkari, Asko Järvinen, and Olli Vapalahti
Author affiliations: University of Helsinki, Helsinki, Finland (P.M. Kinnunen, J.M. Holopainen, H. Piiparinen, T. Sironen, T. Kivelä, J. Virtanen, O. Vapalahti); Finnish Defence Forces, Helsinki (P.M. Kinnunen, H. Hemmilä, H. Piiparinen, S. Nikkari); Helsinki University Hospital, Helsinki (J.M. Holopainen, T. Kivelä, A. Järvinen, O. Vapalahti); Natural Resources Institute Finland (Luke), Vantaa, Finland (J. Niemimaa)

Main Article

Figure

A phylogenetic tree of orthopoxviruses constructed on the basis of the hemagglutinin gene; boldface indicates the CPXV strain infecting the patient described in this article. The phylogeny shows that the sequence derived from this patient represents a locally circulating strain that shares ancestry with a few other CPXV-strains and vaccinia virus. A maximum-likelihood tree was built with 1,000 bootstraps in MEGA 6.06 software (http://www.megasoftware.net/). MEGA was used to estimate the best nuc

Figure. Phylogenetic tree of orthopoxviruses constructed on the basis of the hemagglutinin gene; boldface indicates the CPXV strain infecting the patient described in this article. The phylogeny shows that the sequence derived from this patient represents a locally circulating strain that shares ancestry with a few other CPXV strains and vaccinia virus. A maximum-likelihood tree was built with 1,000 bootstraps in MEGA 6.06 software (http://www.megasoftware.net/). MEGA was used to estimate the best nucleotide substitution model (general time reversible plus invariable sites). The sequence dataset was compiled from the Virus Pathogen Resource database (http://www.viprbrc.org) and aligned by using MUSCLE (http://www.ebi.ac.uk/Tools/msa/muscle/). Scale bar indicates nucleotide submissions per site. CPXV, cowpox virus.

Main Article

Page created: November 17, 2015
Page updated: November 17, 2015
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