Volume 21, Number 2—February 2015
CME ACTIVITY - Research
pH Level as a Marker for Predicting Death among Patients with Vibrio vulnificus Infection, South Korea, 2000–2011
Na Ra Yun, Dong-Min Kim
, Jun Lee, and Mi Ah Han
, Jun Lee, and Mi Ah Han
Table 2
Laboratory results 34 patients in a study looking for predictors of death among persons with Vibrio vulnificus infection, South Korea, 2000–2011*
| Variable | Reference values | Values for patients |
p value | |
|---|---|---|---|---|
| Nonsurvivors, n = 16 | Survivors, n = 18 | |||
| Hematologic values | ||||
| Leukocyte count/μL | 4,000–8,000 | 6,721 (1,030–25,950) | 9,687 (1,940–21,770) | 0.167 |
| Hemoglobin, g/dL | 12.0–16.0 | 12.5 (7.3–17.8) | 11.5 (8.2–15.5) | 0.248 |
| Platelets, 103/μL | 150–400 | 62 (13–147) | 81 (13–243) | 0.330 |
| PT, s | 9.4–12.5 | 17.7 (10.5–30.4) | 14.9 (10.2–19.5) | 0.111 |
| aPTT, s |
28.0–44.0 |
48.5 (28.8–103.0) |
37.4 (21.5–57.5) |
0.040 |
| Arterial blood gas analysis values | ||||
| pH | 7.350–7.450 | 7.08 (6.82–7.36) | 7.41 (7.22–7.50) | <0.001 |
| HCO3, mmol/L | 21.0–28.0 | 8.4 (3.6–13.9) | 18.6 (8.7–25.6) | <0.001 |
| PO2, mm Hg | 83.0–108.0 | 103.4 (69.2–157.0) | 86.6 (52.3–162.8) | 0.035 |
| PCO2, mm Hg |
35.0–45.0 |
26.7 (14.3–41.0) |
28.8 (21.6–38.0) |
0.314 |
| Clinical chemistry values | ||||
| Albumin, g/dL | 3.50–5.20 | 2.63 (2.07–3.00) | 2.82 (1.66–3.84) | 0.201 |
| BUN, mg/dL | 8.0–20.0 | 31.8 (10.0–56.9) | 22.6 (9.6–49.7) | 0.043 |
| Creatinine, mg/dL | 0.5–1.3 | 3.59 (1.52–5.90) | 1.76 (0.60–3.90) | <0.001 |
| Glucose, mg/dL | 60–109 | 134 (22–306) | 141 (40–300) | 0.764 |
| Bilirubin, mg/dL |
0.2–1.2 |
7.5 (0.5–48.3) |
2.3 (0.5–4.1) |
0.094 |
| Liver enzyme values | ||||
| AST, IU/L | 5–40 | 443 (43–1,696) | 111 (30–323) | 0.006 |
| ALT, IU/L |
5–40 |
100 (22–290) |
57 (17–133) |
0.020 |
| APACHE II score | 18 (10–31) | 14 (10–32) | 0.036 | |
*Data are expressed as median (range). ALT, alanine aminotransferase; APACHE, Acute Physiology and Chronic Health Evaluation; aPTT, activated partial thromboplastin time; AST, aspartate aminotransferase; BUN, blood urea nitrogen; HCO3, serum bicarbonate; PCO2, carbon dioxide partial pressure; PO2, partial pressure of oxygen; PT, prothrombin time.
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