TY - JOUR AU - Marzi, Andrea AU - Feldmann, Friederike AU - Geisbert, Thomas AU - Feldmann, Heinz AU - Safronetz, David T1 - Vesicular Stomatitis Virus–Based Vaccines against Lassa and Ebola Viruses T2 - Emerging Infectious Disease journal PY - 2015 VL - 21 IS - 2 SP - 305 SN - 1080-6059 AB - We demonstrated that previous vaccination with a vesicular stomatitis virus (VSV)–based Lassa virus vaccine does not alter protective efficacy of subsequent vaccination with a VSV-based Ebola virus vaccine. These findings demonstrate the utility of VSV-based vaccines against divergent viral pathogens, even when preexisting immunity to the vaccine vector is present. KW - vesicular stomatitis virus KW - VSV KW - viruses KW - pre-existing immunity KW - viral hemorrhagic fever KW - vaccines KW - virus-based vaccines KW - Lassa virus KW - Ebola virus KW - sequential immunization KW - nonhuman primates KW - West Africa KW - sequential vaccination DO - 10.3201/eid2102.141649 UR - https://wwwnc.cdc.gov/eid/article/21/2/14-1649_article ER - End of Reference