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Volume 21, Number 4—April 2015
Research

Population Structure and Antimicrobial Resistance of Invasive Serotype IV Group B Streptococcus, Toronto, Ontario, Canada

Sarah Teatero, Allison McGeer, Aimin Li, Janice Gomes, Christine Seah, Walter Demczuk, Irene Martin, Jessica Wasserscheid, Ken Dewar, Roberto G. Melano, and Nahuel FittipaldiComments to Author 
Author affiliations: Public Health Ontario, Toronto, Ontario, Canada (S. Teatero, A. Li, J. Gomes, C. Seah, R.G. Melano, N. Fittipaldi); University of Toronto, Toronto (A. McGeer, R.G. Melano, N. Fittipaldi); Mount Sinai Hospital, Toronto (A. McGeer, R.G. Melano); Public Health Agency of Canada, Winnipeg, Manitoba, Canada (W. Demczuk, I. Martin); McGill University, Montreal, Quebec, Canada (J. Wasserscheid, K. Dewar); Genome Quebec Innovation Centre, Montreal (J. Wasserscheid, K. Dewar)

Main Article

Figure 1

Inferred genetic relationships of invasive serotype IV group B Streptococcus (GBS), Toronto, Ontario, Canada. A) Neighbor-joining phylogenetic tree constructed by using the concatenated sequences of the 7 gene loci (sdhA, adhP, tkt, glcK, atr, pheS, and glnA) used in the multilocus sequence typing (MLST) scheme for GBS. Each circle represents a single MLST sequence type (ST); circle colors differentiate the 6 STs found among strains in our collection and their sizes are proportional to the numbe

Figure 1. Inferred genetic relationships of invasive serotype IV group B Streptococcus (GBS), Toronto, Ontario, Canada. A) Neighbor-joining phylogenetic tree constructed by using the concatenated sequences of the 7 gene loci (sdhA, adhP, tkt, glcK, atr, pheS, and glnA) used in the multilocus sequence typing (MLST) scheme for GBS. Each circle represents a single MLST sequence type (ST); circle colors differentiate the 6 STs found among strains in our collection and their sizes are proportional to the number of isolates. B) Neighbor-joining phylogenetic analysis based on concatenated sequences of 316 nonredundant single-nucleotide polymorphism (SNP) loci identified by whole-genome sequencing relative to the core genome ST-452 reference strain NGBS572, which shows further diversity within ST-452. C) Diversity within ST-459 serotype IV GBS shown by neighbor-joining phylogenetic analysis based on concatenated sequences of 526 nonredundant SNP loci relative to the core genome of ST-459 reference strain NGBS061. Scale bars indicate nucleotide substitutions per site.

Main Article

Page created: April 02, 2015
Page updated: April 02, 2015
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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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