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Volume 21, Number 5—May 2015
Research

Protective Antibodies against Placental Malaria and Poor Outcomes during Pregnancy, Benin

Nicaise Tuikue NdamComments to Author , Lise Denoeud-Ndam, Justin Doritchamou, Firmine Viwami, Ali Salanti, Morten A. Nielsen, Nadine Fievet, Achille Massougbodji, Adrian J.F. Luty, and Philippe Deloron
Author affiliations: Institut de Recherche pour le Développement, Paris, France (N. Tuikue Ndam, L. Denoeud-Ndam, J. Doritchamou, N. Fievet, A.J.F. Luty, P. Deloron); Pôle de Recherche et d’Enseignement Supérieur Sorbonne Paris Cité, Paris (N.Tuikue Ndam, N. Fievet, A.J.F. Luty, P. Deloron),; Université d’Abomey-Calavi, Cotonou, Benin (F. Viwami, A. Massougbodji, A.J.F. Luty); University of Copenhagen, Copenhagen, Denmark (A. Salanti, M.A. Nielsen)

Main Article

Figure 1

Antibody levels at study inclusion and delivery, by parity, against placental malaria in pregnant women, Benin. A) Apical membrane antigen 1 (AMA-1); B–F) Duffy binding-like (DBL) antigen; G) Full-length ectodomain of variant surface antigen 2 chondroitin sulfate (FV2); H) Variant surface antigen (VSA). Solid circles indicate medians for inclusion, solid squares indicate medians for delivery, and error bars indicate interquartile ranges. AU, absorbance units; rMFI, relative median fluorescence i

Figure 1. Antibody levels at study inclusion and delivery, by parity, against placental malaria in pregnant women, Benin. A) Apical membrane antigen 1 (AMA-1); B–F) Duffy binding-like (DBL) antigen; G) Full-length ectodomain of variant surface antigen 2 chondroitin sulfate (FV2); H) Variant surface antigen (VSA). Solid circles indicate medians for inclusion, solid squares indicate medians for delivery, and error bars indicate interquartile ranges. AU, absorbance units; rMFI, relative median fluorescence intensity. *Parity dependence at inclusion (p<0.05 by Fisher exact test). †Parity dependence at delivery (p<0.05 by Fisher exact test). ‡Decrease between inclusion and delivery (p<0.05 by paired Wilcoxon test). §Increase between inclusion and delivery (p<0.05 by paired Wilcoxon test).

Main Article

Page created: April 17, 2015
Page updated: April 17, 2015
Page reviewed: April 17, 2015
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