Volume 21, Number 5—May 2015
Research
Protective Antibodies against Placental Malaria and Poor Outcomes during Pregnancy, Benin
Table 1
Characteristics of 710 women and their infants in study of protective antibodies against placental malaria and poor outcomes during pregnancy, Benin*
Characteristic | Value |
---|---|
At enrollment | |
Study center, no. (%) | |
Akodeha | 279 (39) |
Comé | 266 (38) |
Wedeme Pedah | 165 (23) |
Age, y, mean ± SD, n = 698 | 26.7 ± 6.3 |
Gravidity, no. (%) | |
Primigravidae | 115 (16) |
Secundigravidae | 154 (22) |
Multigravidae | 441 (62) |
Gestational age, wk, mean ± SD | 16.6 ± 4.8 |
HIV status | |
Positive, no. (%) | 13 (1.8) |
Negative, no. (%) | 697 (98.2) |
Hb level, g/dL, mean ± SD, n = 704 | 10.6 ± 1.3 |
Anemia (Hb level <11 g/dL), no. (%), n = 704 | 439 (62) |
Malaria infection, no. (%)† |
116 (16) |
During follow-up | |
No. antenatal visits, median (IQR) | 5 (4–6) |
Anemia during follow-up, no. (%), n = 708 | 619 (87) |
No. malaria infections during follow-up, no. (%)† | |
0 | 384 (54) |
1 | 183 (26) |
2 | 89 (12) |
>3 | 54 (8) |
Treatment for malaria other than IPTp-SP, no. (%)‡ |
88 (12) |
At delivery | |
Twin delivery, no. (%) | 16 (2) |
Birthweight, g, mean ± SD, n = 679§ | 3,002 ± 486 |
Low birthweight infant (<2,500 g), no. (%), n = 679§ | 71 (10) |
Gestational age, wk, mean ± SD, n = 680§ | 39.6 ± 2.0 |
Small for gestational age, no. (%), n = 612§ | 100 (16) |
Preterm birth (age <37 wk), no. (%), n = 680§ | 53 (8) |
Hb level, g/dL, mean ± SD, n = 649 | 11.0 ± 1.4 |
Anemia (Hb level <11 g/dL), no. (%), n = 649 | 289 (45) |
Placental malaria detected by blood smear, no. (%), n = 60 | 70 (12) |
*Hb, hemoglobin; IQR, interquartile range; IPTp-SP, intermittent preventive treatment in pregnancy with sulfadoxine/pyrimethamine.
†Defined by a positive blood smear regardless of symptoms.
‡82 women received quinine and 6 received other antimalarial medications.
§Excluding twins and stillbirths.