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Volume 22, Number 11—November 2016
Research

Immune Responses to Invasive Group B Streptococcal Disease in Adults

Morven S. EdwardsComments to Author , Marcia A. Rench, C. Daniela Rinaudo, Monica Fabbrini, Giovanna Tuscano, Giada Buffi, Erika Bartolini, Stefano Bonacci, Carol J. Baker, and Immaculada Margarit
Author affiliations: Baylor College of Medicine, Houston, Texas, USA (M.S. Edwards, M.A. Rench, C.J. Baker); GSK Vaccines, S.r.l., Siena, Italy (C.D. Rinaudo, M. Fabbrini, G. Tuscano, G. Buffi, E. Bartolini, S. Bonacci, I. Margarit)

Main Article

Figure 4

Pilus-specific antibody responses in acute- and convalescent-phase serum from patients infected with group B streptococcal strains expressing pilus type 1 or type 2a, Houston, Texas, USA. Anti-pilus–specific IgG titers were measured by multiplex immunoassay that used recombinant pilus proteins coupled to magnetic beads and expressed in RLU/mL. Horizonal bars represent the median (± interquartile range) within each population. For both comparisons, anti-pilus IgG increased significantly in serum

Figure 4. Pilus-specific antibody responses in acute- and convalescent-phase serum from patients infected with group B streptococcal strains expressing pilus type 1 or type 2a, Houston, Texas, USA. Anti-pilus–specific IgG titers were measured by multiplex immunoassay that used recombinant pilus proteins coupled to magnetic beads and expressed in RLU/mL. Horizonal bars represent the median (± interquartile range) within each population. For both comparisons, anti-pilus IgG increased significantly in serum collected during the acute and convalescent phases (p<0.001). p values were calculated by t-test on log-transformed data. Conv, convalescent; RLU, relative Luminex units.

Main Article

Page created: October 18, 2016
Page updated: October 18, 2016
Page reviewed: October 18, 2016
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