Volume 22, Number 2—February 2016
Randomized Controlled Trial of Hospital-Based Hygiene and Water Treatment Intervention (CHoBI7) to Reduce Cholera
|Household contact characteristic||No. (%) contacts
||Odds ratio (95% CI)||p value*|
|Control arm||Intervention arm|
|Culture results available||160 (100)||160 (100)||–||–|
|Negative for V. cholerae infection at baseline||148 (93)||140 (88)||1.15 (0.88–1.51)||0.30|
|Initial V. cholerae infections during the intervention period||20 (14)||10 (7)||0.50 (0.21–1.18)||0.11|
|Initial symptomatic V. cholerae infections during intervention period†||8 (5)||0||0.00 (0–0.623)‡||0.006§|
*Calculated with logistic regression model by using generalized estimating equations to account for clustering within study households.
†Symptomatic infection defined as a V. cholerae–infected household contact with diarrhea or vomiting in the past 48 hours.
‡To calculate exact 95% CIs, an algorithm was used to invert household-level test statistics.
§Fisher exact test calculated at the household level.