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Volume 22, Number 2—February 2016
Dispatch

Bordetella pertussis Strain Lacking Pertactin and Pertussis Toxin

Margaret M. WilliamsComments to Author , Kathryn Sen, Michael R. Weigand, Tami H. Skoff, Victoria A. Cunningham, Tanya A. Halse, M. Lucia Tondella, and CDC Pertussis Working Group
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M.M. Williams, M.R. Weigand, T.H. Skoff, M.L. Tondella); New York State Department of Health, Albany, New York, USA (K.A. Sen); Livingston County Health Department, Mt. Morris, New York, USA (V.A. Cunningham); Wadsworth Center, Albany (T.A. Halse)

Main Article

Table 2

Genes in Bordetella pertussis vaccine strain Tohama I deleted from B. pertussis I979 and FR3749 genomes, including the entire ptx/ptl operon*

Protein ID, GenBank accession no. Gene Product
NP_882281.1 Hypothetical protein
NP_882282.1 ptxA Pertussis toxin subunit 1
NP_882283.1 ptxB Pertussis toxin subunit 2
NP_882284.1 ptxD Pertussis toxin subunit 4
NP_882285.1 ptxE Pertussis toxin subunit 5
NP_882286.1 ptxC Pertussis toxin subunit 3
NP_882287.1 ptlA Type IV secretion system protein PtlA
NP_882288.1 ptlB Type IV secretion system protein PtlB
NP_882289.1 ptlC Type IV secretion system protein PtlC
NP_882290.1 ptlD Type IV secretion system protein PtlD
NP_882291.1 ptlI Type IV secretion system protein PtlI
NP_882292.1 ptlE Type IV secretion system protein PtlE
NP_882293.1 ptlF Type IV secretion system protein PtlF
NP_882294.1 ptlG Type IV secretion system protein PtlG
NP_882295.1 ptlH Type IV secretion system protein PtlH
tRNA-Asn
NP_882296.1 Membrane protein
NP_882297.1 AraC family transcriptional regulator
NP_882298.1 Hypothetical protein
NP_882299.1 Membrane protein
NP_882300.1 Hypothetical protein
NP_882301.1 Peptide ABC transporter substrate binding protein
NP_882302.1 Transport system permease
NP_882303.1 Transport system permease
Pseudogene
NP_882304.1 IS481 Transposase
NP_882305.1 argJ Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase
NP_882306.1 Hypothetical protein
NP_882307.1 Hypothetical protein
NP_882308.1 IS1002 Transposase

*ID, identification; ptx, pertussis toxin gene; ptl, pertussis toxin liberation gene.

Main Article

1Members of the CDC Pertussis Working Group are listed at the end of this article.

Page created: January 15, 2016
Page updated: January 15, 2016
Page reviewed: January 15, 2016
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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