Figure 1. Pathologic alterations in piglets infected with Senecavirus A, Brazil, 2015. Gross examination shows multifocal diphtheric glossitis (A) and ulcerations of the coronary band (B). Histopathologic images demonstrate ballooning degeneration of the epithelium of the tongue (C) and positive immunoreactivity of the uroepithelium of the urinary bladder (D) to Senecavirus A. Panel B, scale shown in centimeters; panel C, hematoxylin and eosin stain; scale bar indicates 20 μm; panel D, immunoperoxidase; scale bar indicates 10 μm.