TY - JOUR AU - Haviari, Skerdi AU - Cassier, Pierre AU - Dananché, Cédric AU - Hulin, Monique AU - Dauwalder, Olivier AU - Rouvière, Olivier AU - Bertrand, Xavier AU - Perraud, Michel AU - Bénet, Thomas AU - Vanhems, Philippe T1 - Outbreak of Achromobacter xylosoxidans and Ochrobactrum anthropi Infections after Prostate Biopsies, France, 2014 T2 - Emerging Infectious Disease journal PY - 2016 VL - 22 IS - 8 SP - 1412 SN - 1080-6059 AB - We report an outbreak of healthcare-associated prostatitis involving rare environmental pathogens in immunocompetent patients undergoing transrectal prostate biopsies at Hôpital Édouard Herriot (Lyon, France) during August 13–October 10, 2014. Despite a fluoroquinolone-based prophylaxis, 5 patients were infected with Achromobacter xylosoxidans and 3 with Ochrobactrum anthropi, which has not been reported as pathogenic in nonimmunocompromised persons. All patients recovered fully. Analysis of the outbreak included case investigation, case–control study, biopsy procedure review, microbiologic testing of environmental and clinical samples, and retrospective review of hospital records for 4 years before the outbreak. The cases resulted from asepsis errors during preparation of materials for the biopsies. A low-level outbreak involving environmental bacteria was likely present for years, masked by antimicrobial drug prophylaxis and a low number of cases. Healthcare personnel should promptly report unusual pathogens in immunocompetent patients to infection control units, and guidelines should explicitly mention asepsis during materials preparation. KW - Achromobacter xylosoxidans KW - Achromobacter denitrificans KW - Ochrobactrum anthropi KW - disease outbreaks KW - prostate KW - prostatitis KW - prostatic diseases KW - diagnostic techniques KW - clinical laboratory techniques KW - surgical KW - biopsy KW - gram-negative bacteria KW - bacteria KW - France DO - 10.3201/eid2208.151423 UR - https://wwwnc.cdc.gov/eid/article/22/8/15-1423_article ER - End of Reference