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Volume 22, Number 8—August 2016
Research

Phylogeographic Evidence for 2 Genetically Distinct Zoonotic Plasmodium knowlesi Parasites, Malaysia

Ruhani Yusof1, Md Atique Ahmed1, Jenarun Jelip, Hie Ung Ngian, Sahlawati Mustakim, Hani Mat Hussin, Mun Yik Fong, Rohela Mahmud, Frankie Anak Thomas Sitam, J. Rovie-Ryan Japning, Georges Snounou, Ananias A. Escalante, and Yee Ling LauComments to Author 
Author affiliations: University of Malaya Faculty of Medicine, Kuala Lumpur, Malaysia (R. Yusof, M.A. Ahmed, M.Y. Fong, R. Mahmud, Y.L. Lau); Sabah State Health Department, Sabah, Malaysia (J. Jelip); Hospital Kapit, Sarawak, Malaysia (H.U. Ngian); Hospital Tengku Microbiology Laboratory, Ampuan Rahimah, Selangor, Malaysia (S. Mustakim); Kelantan State Health Department, Kelantan, Malaysia (H.M. Hussin); Department of Wildlife and National Parks Peninsular Malaysia, Kuala Lumpur, Malaysia (F.A.T. Sitam, J. Rovie-Ryan); Sorbonne Universités, INSERM, Paris, France (G. Snounou); Temple University, Philadelphia, PA, USA (G. Snounou, A.A. Escalante)

Main Article

Table 4

Results of statistical testing for neutrality of Plasmodium knowlesi parasite populations in Malaysia

Gene and location
Tajima D (23)
Fu and Li D (24)
Fu and Li F (25)
Fu Fs (26)
PkA-type 18S rRNA
Peninsular Malaysia –2.49764* –3.71579 † –3.85230 † –56.133
Malaysian Borneo –2.73586* –6.47796 † –5.87592 † –59.698
Overall
–2.71801*
–7.08484†
–5.97285†
–151.882
PkCOX1
Peninsular Malaysia –2.06554‡ –3.20519‡ –3.33283† –18.092
Malaysian Borneo –2.28662† –3.60846† –3.71725† –27.990
Overall –2.02607‡ –4.40748† –4.11218† –48.131

*PkA-type 18S rRNA, P. knowlesi type A small subunit ribosomal 18S RNA; PkCOX1 P. knowlesi cytochrome oxidase subunit I.
*p<0.001.
†p<0.02.
‡p<0.05.

Main Article

1These authors contributed equally to this article.

Page created: July 15, 2016
Page updated: July 15, 2016
Page reviewed: July 15, 2016
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