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Volume 22, Number 9—September 2016
Research

Prediction of Protection against Asian Enterovirus 71 Outbreak Strains by Cross-neutralizing Capacity of Serum from Dutch Donors, The Netherlands

Sabine M.G. van der SandenComments to Author , Gerrit Koen, Hetty van Eijk, Sylvie M. Koekkoek, Menno D. de Jong, and Katja C. Wolthers
Author affiliations: Academic Medical Center, Amsterdam, the Netherlands

Main Article

Figure 4

Amino acid sequence comparison of the capsid regions of EV-71 strains used for serologic analysis of strains isolated in Asia and Europe in study of immunity to these strains after exposure to IVIg from viruses from the Netherlands. Residues 164, 240, and 241 of VP1 (differing among genogroup B and C viruses and located in known antigenic sites) and residues that differ among neutralizable and nonneutralizable strains are marked by boxes. Known epitopes and antigenic determinants for EV-71 are m

Figure 4. Amino acid sequence comparison of the capsid regions of EV-71 strains used for serologic analysis of strains isolated in Asia and Europe in study of immunity to these strains after exposure to IVIg from viruses from the Netherlands. Residues 164, 240, and 241 of VP1 (differing among genogroup B and C viruses and located in known antigenic sites) and residues that differ among neutralizable and nonneutralizable strains are marked by boxes. Known epitopes and antigenic determinants for EV-71 are marked in gray (22–25). EV-71, enterovirus 71; IVIg, intravenous immunoglobulin; VN, Vietnam; VP, viral protein.

Main Article

Page created: August 16, 2016
Page updated: August 16, 2016
Page reviewed: August 16, 2016
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