TY - JOUR AU - Houseman, Catherine AU - Hughes, Gareth AU - Chapman, Kaye AU - Wilson, Deborah AU - Gorton, Russell T1 - Increased Invasive Pneumococcal Disease, North East England, UK T2 - Emerging Infectious Disease journal PY - 2017 VL - 23 IS - 1 SP - 122 SN - 1080-6059 AB - Since April 2014, invasive pneumococcal disease incidence has increased substantially across North East England, United Kingdom, reversing the decline that followed the 2006 introduction of pneumococcal conjugate vaccines. Significant increases occurred in 23-valent polysaccharide vaccine serotypes and nonvaccine serotypes. Trends in other regions and long-term effects of multivalent vaccines require further investigation. KW - Streptococcus pneumoniae KW - pneumococcal infections KW - invasive pneumococcal disease KW - pneumococcal polysaccharide vaccine KW - PCV13 vaccine KW - incidence KW - bacteria KW - England KW - vaccines KW - United Kingdom DO - 10.3201/eid2301.160897 UR - https://wwwnc.cdc.gov/eid/article/23/1/16-0897_article ER - End of Reference