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Volume 23, Number 12—December 2017
CME ACTIVITY - Research

Group B Streptococcus Infections Caused by Improper Sourcing and Handling of Fish for Raw Consumption, Singapore, 2015–2016

Man L. Chau1, Swaine L. Chen1, Min Yap, Sri H.P. Hartantyo, Paul K.T. Chiew, Charlene J. Fernandez, Wai K. Wong, Rockey K. Fong, Wei L. Tan, Brian Z.Y. Tan, Youming Ng, Kyaw T. Aung, Kurosh S. Mehershahi, Christopher Goh, Joanne S.L. Kang, Timothy Barkham, Adeline O.K. Leong, Ramona A. Gutiérrez, and Lee C. NgComments to Author 
Author affiliations: National Environment Agency, Singapore (M.L. Chau, M. Yap, S.H.P. Hartantyo, Y. Ng, K.T. Aung, C. Goh, J.S.L. Kang, A.O.K. Leong, R.A. Gutiérrez, L.C. Ng); Genome Institute of Singapore, Singapore (S.L. Chen); National University of Singapore, Singapore (S.L. Chen, K.S. Mehershahi); Agri-Food and Veterinary Authority of Singapore, Singapore (P.K.T. Chiew, C.J. Fernandez, W.K. Wong, R.K. Fong, W.L. Tan, B.Z.Y. Tan); Nanyang Technological University, Singapore (P.K.T. Chiew, L.C. Ng); Tan Tock Seng Hospital, Singapore (T. Barkham)

Main Article

Figure 4

Phylogenetic analysis of group B Streptococcus (GBS) infections caused by improper sourcing and handling of raw fish for raw consumption, Singapore, 2015–2016. A) Maximum-likelihood single-nucleotide polymorphism (SNP)–based tree for GBS ST283 strains relative to the SG-M1 reference human outbreak strain. Year, location, and source (human or fish) for isolates are indicated. Twelve strains from 6 fish (SGEHI2015-NWC941, SGEHI2015–95, LG01, LG02, LG04, and LG06) and 4 fish tank water samples (LG0

Figure 4. Phylogenetic analysis of group B Streptococcus (GBS) infections caused by improper sourcing and handling of raw fish for raw consumption, Singapore, 2015–2016. A) Maximum-likelihood single-nucleotide polymorphism (SNP)–based tree for GBS ST283 strains relative to the SG-M1 reference human outbreak strain. Year, location, and source (human or fish) for isolates are indicated. Twelve strains from 6 fish (SGEHI2015-NWC941, SGEHI2015–95, LG01, LG02, LG04, and LG06) and 4 fish tank water samples (LG07, LG08, LG09, and LG11) were nearly identical to the local reference outbreak strain SG-M1 (no SNP, 0 and 12 indels, respectively). Scale bar indicates distance over 4,093 total SNPs. B) Enlargement of blue subtree from bottom of tree in panel A showing fish GBS ST283 isolates that were different (57–71 SNPs and 11–33 indels) from the human outbreak strain. ST, sequence type.

Main Article

1These authors contributed equally to this article.

Page created: November 15, 2017
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