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Volume 23, Number 4—April 2017

Transmission of Hepatitis A Virus through Combined Liver–Small Intestine–Pancreas Transplantation

Monique A. FosterComments to Author , Lauren M. Weil, Sherry Jin, Thomas Johnson, Tonya R. Hayden-Mixson, Yury Khudyakov, Pallavi D. Annambhotla, Sridhar V. Basavaraju, Saleem Kamili, Jana M. Ritter, Noele Nelson, George Mazariegos, Michael Green, Ryan W. Himes, David T. Kuhar, Matthew J. Kuehnert, Jeffrey R. Miller, Rachel Wiseman, and Anne C. Moorman
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M.A. Foster, T.R. Hayden-Mixson, Y. Khudyakov, P.D. Annambhotla, S.V. Basavaraju, S. Kamili, J.M. Ritter, N. Nelson, D.T. Kuhar, M.J. Kuehnert, J.A. Miller, A.C. Moorman); Texas Department of State Health Services, Austin, Texas, USA (L.M. Weil); Harris County Public Health and Environmental Services, Houston, Texas, USA (S. Jin); Houston Health Department, Houston (T. Johnson); Children’s Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA (G. Mazariegos, M. Green); Texas Children’s Hospital, Houston, (R.W. Himes); Pennsylvania Department of Health, Harrisburg, Pennsylvania, USA (J.A. Miller); Texas Department of State Health Services, Austin (R. Wiseman)

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Table 2

Pathologic, serum, and fecal HAV RNA quantification test results of multi–visceral organ recipient, Texas, 2014–2015*

Date collected Liver HAV RNA, IU/mL Small bowel HAV RNA, IU/mL Serum HAV RNA, IU/mL Fecal HAV RNA, IU/mL
2014 Dec 18 Native liver, none detected
2014 Dec 23 34,000
2015 Jan 23 1,500,00
2015 Feb 10 7,000
2015 Mar 10 5,400
2015 Apr 16 >90,000,000
2015 Sep 21 >90,000,000 >90,000,000
2015 Sep 29 746,000,000 >90,000,000
2015 Oct 15 1,400,000 372,000
2015 Nov 9 27,900
2015 Nov 16 17,300
2015 Nov 23 13,000 1,500,000
2015 Dec 3 38,900 51,900
2016 Jan 11 68,000 22,600
2016 Mar 9 320
2016 Apr 6 Not detected 270
2016 May 4 Not detected Not detected

*Blank cells indicate that no specimen was available for testing. HAV, hepatitis A virus.

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Page created: March 13, 2017
Page updated: March 13, 2017
Page reviewed: March 13, 2017
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.