Brucella neotomae Infection in Humans, Costa Rica
Marcela Suárez-Esquivel, Nazareth Ruiz-Villalobos, César Jiménez-Rojas, Elías Barquero-Calvo, Carlos Chacón-Díaz, Eunice Víquez-Ruiz, Norman Rojas-Campos, Kate S. Baker1
, Gerardo Oviedo-Sánchez, Ernesto Amuy, Esteban Chaves-Olarte, Nicholas R. Thomson, Edgardo Moreno, and Caterina Guzmán-Verri
Author affiliations: Universidad Nacional, Heredia, Costa Rica (M. Suárez-Esquivel, N. Ruiz-Villalobos, C. Jiménez-Rojas, E. Barquero-Calvo, E. Víquez-Ruiz, E. Moreno, C. Guzmán-Verri); Universidad de Costa Rica, San José, Costa Rica (E. Barquero-Calvo, C. Chacón-Díaz, N. Rojas-Campos, G. Oviedo-Sánchez, E. Chaves-Olarte, E. Moreno, C. Guzmán-Verri); Wellcome Trust Sanger Institute, Hinxton, UK (K.S. Baker, N.R. Thomson); Caja Costarricense del Seguro Social, Puntarenas, Costa Rica (E. Amuy)
Figure 2. Phylogenetic tree based on 34,307 single-nucleotide polymorphisms (SNPs) found among 51 Brucella genome sequences. The clinical isolates bneohCR1 and bneohCR2 cluster with B. neotomae 5K33 and differ by 164 SNPs. A different color is used to represent each Brucella species. Dotted red lines denote the 3 B. neotomae isolates, which overlap at the tip of the branch because of the high identity among them.
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