Volume 23, Number 6—June 2017
Research
Invasive Serotype 35B Pneumococci Including an Expanding Serotype Switch Lineage, United States, 2015–2016
Sopio Chochua, Benjamin J. Metcalf, Zhongya Li, Hollis Walker, Theresa Tran, Lesley McGee, and Bernard Beall
Table 3
Annual incidence and proportions of penicillin-nonsusceptible 35B pneumococcal isolates causing IPD, United States, 1999–2015*
| Year | Surveillance population | % CIS | No. 35B isolates from patients by age, y |
Relative incidence of 35B IPD† | Pen MIC, μg/mL |
penNS 35B isolates/penS 35B isolates | |||
|---|---|---|---|---|---|---|---|---|---|
| <5 | ≥5 | >2 | 0.12−1 | <0.06 | |||||
| 1998 | 17,383,935 | 86.1 | 3 | 18 | 1.40 | 9 | 5 | 7 | 2.0 |
| 1999 | 18,550,681 | 87.0 | 2 | 18 | 1.24 | 8 | 3 | 9 | 1.2 |
| 2000 | 19,821,607 | 86.3 | 4 | 21 | 1.46 | 7 | 9 | 9 | 1.8 |
| 2001 | 22,479,308 | 88.1 | 2 | 40 | 2.12 | 14 | 18 | 10 | 3.2 |
| 2002 | 25,051,246 | 87.6 | 2 | 34 | 1.64 | 20 | 8 | 8 | 3.5 |
| 2003 | 25,264,246 | 91.4 | 11 | 49 | 2.56 | 22 | 26 | 11 | 4.4 |
| 2004 | 27,419,898 | 87.9 | 15 | 69 | 3.49 | 44 | 25 | 15 | 4.6 |
| 2005 | 27,816,784 | 89.5 | 11 | 57 | 2.73 | 35 | 18 | 15 | 3.5 |
| 2006 | 28,204,455 | 86.7 | 1 | 65 | 2.70 | 37 | 15 | 14 | 3.7 |
| 2007 | 28,579,312 | 87.5 | 5 | 83 | 3.52 | 51 | 23 | 14 | 5.3 |
| 2008 | 28,856,774 | 86.7 | 12 | 80 | 3.68 | 62 | 16 | 14 | 5.6 |
| 2009 | 29,206,528 | 89.8 | 8 | 70 | 2.97 | 45 | 16 | 17 | 3.6 |
| 2010 | 29,757,552 | 90.2 | 4 | 67 | 2.65 | 52 | 14 | 5 | 13.2 |
| 2011 | 30,075,050 | 90.3 | 11 | 77 | 3.28 | 71 | 7 | 10 | 7.8 |
| 2012 | 30,356,544 | 90.6 | 13 | 101 | 4.14 | 94 | 14 | 6 | 18.0 |
| 2013 | 30,604,240 | 88.7 | 15 | 114 | 4.75 | 94 | 25 | 10 | 11.9 |
| 2014 | 31,328,211 | 88.2 | 16 | 116 | 4.78 | 104 | 22 | 6 | 21.0 |
| 2015 | 31,977,800 | 92.0 | 10 | 121 | 4.45 | 101 | 24 | 6 | 20.8 |
*CIS, case isolates serotyped; IPD, invasive pneumococcal disease.
†Estimated cases/million = total 35Bs x 100/% CIS surveillance population/1,000,000.
Page created: May 16, 2017
Page updated: May 16, 2017
Page reviewed: May 16, 2017
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