Volume 23, Number 7—July 2017
Research
Concurrent Infection with Hepatitis C Virus and Streptococcus pneumoniae
Thomas J. Marrie, Gregory J. Tyrrell, Sumit R. Majumdar, and Dean T. Eurich1
Table 1
Characteristics of 3,251 IPD patients >17 years of age by HCV status, Alberta, Canada, 2000–2014*
| Characteristic | HCV-positive | HCV-negative | p value |
|---|---|---|---|
| Total no. |
355 (10.9) |
2,896 (89.1) |
|
| Sex | |||
| M | 203 (57.2) | 1,635 (56.5) | 0.810 |
| F |
152 (42.8) |
1,261 (43.5) |
NA |
| Mean (SD) age, y |
45.2 (9) |
55.7 (18.4) |
<0.001 |
| Aboriginal |
95 (26.8) |
355 (11.6) |
<0.001 |
| Residence at time of admission | |||
| Home | 220 (62.0) | 2,408 (83.3) | NA |
| Homeless |
88 (24.8) |
148 (5.0) |
<0.001 |
| Functional status | |||
| Walking independently |
264 (74.4) |
2,107 (72.8) |
0.520 |
| Concurrent condition | |||
| HIV infection | 81 (22.8) | 55 (1.9) | <0.001 |
| Cancer in past 5 y | 19 (5.4) | 385 (13.4) | <0.001 |
| Diabetes | 17 (4.8) | 179 (6.1) | 0.300 |
| Coronary heart disease | 16 (4.5) | 437 (15.1) | <0.001 |
| Chronic obstructive pulmonary disease | 32 (9.0) | 532 (18.4) | <0.001 |
| Cirrhosis | 86 (24.2) | 91 (3.1) | <0.001 |
| >2 other chronic conditions |
160 (45.1) |
1,354 (46.8) |
0.550 |
| Lifestyle factors | |||
| Current smoker | 245 (69) | 1,222 (42.2) | <0.001 |
| Illicit drug use | 236 (66.5) | 323 (11.1) | <0.001 |
| Alcoholism | 217 (61.1) | 568 (19.6) | <0.001 |
*Values are no. (%) unless otherwise indicated. HCV, hepatitis C virus; IPD, invasive pneumococcal disease; NA, not applicable.
1All authors contributed equally to this article.
Page created: June 19, 2017
Page updated: June 19, 2017
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