Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 23, Number 9—September 2017
Dispatch

Emergence of Plasmid-Mediated Fosfomycin-Resistance Genes among Escherichia coli Isolates, France

Yahia Benzerara, Salah Gallah, Baptiste Hommeril, Nathalie Genel, Dominique Decré, Martin Rottman, and Guillaume ArletComments to Author 
Author affiliations: Assistance Publique des Hôpitaux de Paris Hôpitaux Universitaires Est Parisiens Paris, France (Y. Benzerara, S. Gallah, B. Hommeril, D. Decré, G. Arlet); Université Pierre et Marie Curie, Sorbonne Université, Paris (N. Genel, D. Decré, G. Arlet); Assistance Publique des Hôpitaux de Paris Hôpitaux Universitaires Paris Ile de France Ouest, Hôpital Raymond Poincaré, Garches, France (M. Rottman); Université de Versailles Saint-Quentin-en-Yvelines, St-Quentin en Yvelines, France (M. Rottman)

Main Article

Figure

Inhibition of FosA-mediated fosfomycin resistance by phosphonoformiate. A modified Kirby-Bauer disk diffusion susceptibility assay was performed. In brief, a Mueller-Hinton agar plate was streaked with a 0.5 McFarland suspension of the isolate assayed. Three disks were placed on the agar: a 200-µg fosfomycin disk (upper left), a 100-µg phosphonoformiate disk (lower center), and a disk with both a 200-µg fosfomycin and 100-µg phosphonoformiate (upper right). The diameter of the growth inhibition

Figure. Inhibition of FosA-mediated fosfomycin resistance by phosphonoformiate. A modified Kirby-Bauer disk diffusion susceptibility assay was performed. In brief, a Mueller-Hinton agar plate was streaked with a 0.5 McFarland suspension of the isolate assayed. Three disks were placed on the agar: 200-µg fosfomycin disk (upper left), a 100-µg phosphonoformiate disk (lower center), and a disk with both a 200-µg fosfomycin and 100-µg phosphonoformiate (upper right). The diameter of the growth inhibition zone around each disk was measured after 18–24 h incubation at 35°C (+2°C). FosA-mediated fosfomycin resistance is inhibited by phosphonoformiate and is demonstrated by an increase in the diameter of the growth inhibition zone by >4 mm.

Main Article

Page created: August 17, 2017
Page updated: August 17, 2017
Page reviewed: August 17, 2017
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external