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Volume 24, Number 10—October 2018

Zika Virus Infection during Pregnancy and Effects on Early Childhood Development, French Polynesia, 2013–2016

Lorenzo Subissi, Timothée Dub, Marianne Besnard, Teheipuaura Mariteragi-Helle, Tuxuan Nhan, Delphine Lutringer-Magnin, Philippe Barboza, Céline Gurry, Pauline Brindel, Eric J. Nilles, David Baud, Angela Merianos, Didier Musso, Judith R. Glynn, Gilles Dupuis, Van-Mai Cao-Lormeau1, Marine Giard1Comments to Author , and Henri-Pierre Mallet1
Author affiliations: World Health Organization, Geneva, Switzerland (L. Subissi, P. Barboza, C. Gurry, P. Brindel); Institut Pasteur, Paris, France (T. Dub); French Polynesia Hospital Center, Pirae, French Polynesia (M. Besnard, D. Lutringer-Magnin); Institut Louis Malardé, Papeete, French Polynesia (T. Mariteragi-Helle, T. Nhan, D. Musso, V.-M. Cao-Lormeau); Brigham and Women’s Hospital and Harvard Humanitarian Initiative, Boston, Massachusetts, USA (E.J. Nilles); World Health Organization, Manila, Philippines (E.J. Nilles, A. Merianos); University Hospital, Lausanne, Switzerland (D. Baud); Aix Marseille University, IRD, AP-HM, SSA, VITROME, IHU-Méditerranée Infection, Marseille, France (D. Musso); London School of Hygiene & Tropical Medicine, London, UK (J.R. Glynn); University of Québec, Montreal, Québec, Canada (G. Dupuis); Centre de Liaison sur l’Intervention et la Prévention Psychosociales, Montreal (G. Dupuis); Bureau de Veille Sanitaire, Direction de la Santé, Papeete (M. Giard, H.-P. Mallet)

Main Article

Table 1

Main and secondary diagnoses for 21 case-patients recruited in case-control study of Zika virus infection during pregnancy and effects on early childhood development, French Polynesia, 2013–2016

Diagnoses No. (%) Pregnancy termination Live births Child alive,* n = 7
Main diagnoses
Microcephaly 7 (33) 4 3 1
Brainstem dysfunction of the neonate 5 (24) 0 5 3
Other CNS congenital defects 9 (43) 6 3 3
Septal and/or corpus callosum agenesis 3 (14) 1 2 2
Intraventricular hemorrhage 1 (5) 0 1 1
Cerebral hemorrhage and placental calcifications 1 (5) 1 1 0
Polymalformative syndrome 2 (10) 2 0 0
Complete or sacral spina bifida
2 (10)
Secondary diagnoses
Ventriculomegaly 6 (29) 4 2 2
Arthrogryposis 3 (14) 3 0 0

*As of July 2017.

Main Article

1These authors contributed equally to this article.

Page created: September 16, 2018
Page updated: September 16, 2018
Page reviewed: September 16, 2018
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