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Volume 24, Number 10—October 2018
Dispatch

Mycobacterium caprae Infection in Captive Borneo Elephant, Japan

Shiomi YoshidaComments to Author , Satomi Suga, Satoshi Ishikawa, Yasuhiko Mukai, Kazunari Tsuyuguchi, Yoshikazu Inoue, Taro Yamamoto, and Takayuki Wada
Author affiliations: Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan (S. Yoshida); National Hospital Organization Kinki-chuo Chest Medical Center Clinical Research Center, Sakai, Japan (S. Yoshida, K. Tsuyuguchi, Y. Inoue); Fukuyama Zoo, Fukuyama, Japan (S. Suga, S. Ishikawa, Y. Mukai); Nagasaki University Institute of Tropical Medicine, Nagasaki (T. Yamamoto, T. Wada); Nagasaki University School of Tropical Medicine and Global Health, Nagasaki (T. Wada)

Main Article

Table 2

Single-nucleotide polymorphism differences between isolates EPDC01 and EPDC02 from a captive Borneo elephant with Mycobacterium caprae infection, Japan, 2016*

Genomic position Gene Mutation Amino acid change Description of function
1,338,135 Rv1194c G → frameshift Gln127 → frameshift Unknown
1,445,272 Rv1290A C → T Ala72 → Val Unknown
2,155,168 katG C → T Ser315 → Asn Catalase; isoniazid resistance
2,577,556 Rv2306A G → A Gly150 → Glu Unknown
3,200,585 Rv2891 T → G Leu107 → Arg Unknown
3,777,062 Rv3365c C → A Gly147 → Val Unknown
4,298,329 pks2 G → A Pro426 → Leu Lipid metabolism
4,345,372 Rv3869 G → C Ala112 → Pro Unknown

*Excluded paralogue genes, which are the descendants of an ancestral gene and underwent a duplication event.

Main Article

Page created: September 16, 2018
Page updated: September 16, 2018
Page reviewed: September 16, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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