Detection and Characterization of Human Pegivirus 2, Vietnam
Nguyen To Anh, Nguyen Thi Thu Hong, Le Nguyen Truc Nhu, Tran Tan Thanh, Catherine Anscombe, Le Ngoc Chau, Tran Thi Thanh Thanh, Chuen-Yen Lau, Direk Limmathurotsakul, Nguyen Van Vinh Chau, H. Rogier van Doorn, Xutao Deng, Motiur Rahman, Eric Delwart, Thuy Le, Guy Thwaites, Le Van Tan
, and for the Southeast Asia Infectious Disease Clinical Research Network
Author affiliations: Oxford University, Ho Chi Minh City, Vietnam (N.T. Anh, N.T.T. Hong, L.N.T. Nhu, T.T. Thanh, C. Anscombe, L.N. Chau, T.T.T. Thanh, H.R. van Doorn, M. Rahman, T. Le, G. Thwaites, L.V. Tan); University of Oxford, Oxford, UK (C. Anscombe, D. Limmathurotsakul, H.R. van Doorn, G. Thwaites); National Institutes of Health, Bethesda, Maryland, USA (C.-Y. Lau); Mahidol Oxford Tropical Research Unit, Bangkok, Thailand (D. Limmathurotsakul); Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam (N.V.V. Chau); Blood Systems Research Institute, San Francisco, California, USA (X. Deng, E. Delwart); University of California, San Francisco (X. Deng, E. Delwart)
Figure. Maximum-likelihood phylogenetic tree of amino acid sequences of coding sequences of human pegivirus 2 strains from Vietnam compared with global strains and other pegiviruses. We used the general matrix with empirical amino acid frequencies, a gamma distribution of 4 rates, and invariant sites, as suggested by IQ TREE (http://www.iqtree.org), to reconstruct the phylogenetic trees. We assessed support for individual nodes using a bootstrap procedure of 10,000 replicates. Scale bar indicates amino acid substitutions per site.
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