TY - JOUR AU - Kayomo, Michel Kaswa AU - Hasker, Epco AU - Aloni, Muriel AU - Nkuku, Léontine AU - Kazadi, Marcel AU - Kabengele, Thierry AU - Muteteke, Dorcas AU - Kapita, François AU - Lufulwabo, Alphonse AU - Mukadi, Ya Diul AU - Muyembe-Tamfum, Jean-Jacques AU - Ieven, Margareta AU - de Jong, Bouke AU - Boelaert, Marleen T1 - Outbreak of Tuberculosis and Multidrug-Resistant Tuberculosis, Mbuji-Mayi Central Prison, Democratic Republic of the Congo T2 - Emerging Infectious Disease journal PY - 2018 VL - 24 IS - 11 SP - 2029 SN - 1080-6059 AB - After an alert regarding ≈31 tuberculosis (TB) cases, 3 of which were rifampin-resistant TB cases, in Mbuji-Mayi Central Prison, Democratic Republic of the Congo, we conducted an outbreak investigation in January 2015. We analyzed sputum of presumptive TB patients by using the Xpert MTB/RIF assay. We also assessed the Mycobacterium tuberculosis isolates’ drug-susceptibility patterns and risk factors for TB infection. Among a prison population of 918 inmates, 29 TB case-patients were already undergoing treatment. We found an additional 475 presumptive TB case-patients and confirmed TB in 170 of them. In March 2015, the prevalence rate of confirmed TB was 21.7% (199/918 inmates). We detected an additional 14 cases of rifampin-resistant TB and initiated treatment in all 14 of these case-patients. Overcrowded living conditions and poor nutrition appeared to be the driving factors behind the high TB incidence in this prison. KW - tuberculosis KW - TB KW - multidrug-resistant KW - MDR-TB KW - incidence KW - DRC KW - prisons KW - Mbuji-Mayi KW - Democratic Republic of Congo KW - tuberculosis and other mycobacteria KW - outbreak KW - MDR TB KW - Xpert MTB/RIF KW - bacteria KW - antimicrobial resistance DO - 10.3201/eid2411.180769 UR - https://wwwnc.cdc.gov/eid/article/24/11/18-0769_article ER - End of Reference