, Christine Fast, Kore Schlottau, Bernd Hoffmann, and Martin Beer
Figure 2. Clinical signs observed in wild boar and pigs and small ruminant morbillivirus (formerly called peste des petits ruminants virus; PPRV) antigen detection in a pig tonsil in experimental study of PPRV transmission, Germany. A) Purulent nasal discharge in wild boar 4 at 8 days after infection; B) diarrhea in wild boar 4 at 7 days after infection; C) swollen eyelids in pig 3 at 10 days after infection; D) PPRV antigen (red) in the tonsil of pig 1 at 30 days after infection (≈22 days after contact infection of pig 1), by immunohistochemical staining with monocloncal mouse anti-PPRV; scale bar indicates 50 μm. Clinical signs in the 3 pigs in trial 1 included a transient rise in body temperature, ruffling bristles, diarrhea, reduced activity and food intake/slight emaciation, swelling of the eyelids, mild to severe conjunctivitis, and mucous to purulent ocular discharge in the first days after infection. In the 4 wild boar in trial 2, clinical signs included transiently increased body temperature, diarrhea (including fresh blood), reduced general condition, inappetence, and mucopurulent nasal discharge. A detailed description of the infection experiments is provided in the Technical Appendix.