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Volume 24, Number 12—December 2018

Rat Hepatitis E Virus as Cause of Persistent Hepatitis after Liver Transplant

Siddharth Sridhar, Cyril C.Y. Yip, Shusheng Wu, Jianpiao Cai, Anna Jin-Xia Zhang, Kit-Hang Leung, Tom W.H. Chung, Jasper F.W. Chan, Wan-Mui Chan, Jade L.L. Teng, Rex K.H. Au-Yeung, Vincent C.C. Cheng, Honglin Chen, Susanna K.P. Lau, Patrick C.Y. Woo, Ning-Shao Xia, Chung-Mau Lo, and Kwok-Yung YuenComments to Author 
Author affiliations: The University of Hong Kong, Hong Kong, China (S. Sridhar, C.C.Y. Yip, S. Wu, J. Cai, A.J.-X. Zhang, K.-H. Leung, T.W.H. Chung, J.F.W. Chan, W.-M. Chan, J.L.L. Teng, R.K.H. Au-Yeung, V.C.C. Cheng, H. Chen, S.K.P. Lau, P.C.Y. Woo, C.-M. Lo, K.-Y. Yuen); The University of Hong Kong–Shenzhen Hospital, Shenzhen, China (J.F.W. Chan, C.-M. Lo, K.-Y. Yuen); Xiamen University, Xiamen, China (N.-S. Xia)

Main Article

Table 1

Demographic and clinical characteristics of solid organ transplant recipients, Queen Mary Hospital, Hong Kong, January 1, 2014–December 31, 2017*

Characteristic Result†
No. transplant recipients
Organ transplanted
Kidney 430 (83.0)
Liver 61 (11.7)
Heart 16 (3.1)
Lung 10 (1.9)
Combined kidney and liver
1 (0.2)
Median age, y
F 203 (39.2)
315 (60.8)
Prevalence of persistent biochemical hepatitis
52 (10.2)
Cause of biochemical hepatitis
Viral hepatitis‡
Reactivation of chronic HBV infection 5 (9.6)
Chronic HCV infection 7 (13.5)
Chronic HEV infection 5 (9.6)
CMV reactivation 8 (15.4)
Nonviral causes†
Drug toxicity 7 (13.5)
Nonalcoholic fatty liver disease 3 (5.8)
Liver graft rejection 7 (13.5)
Biliary anastomotic stricture 5 (9.6)
Liver malignancies 2 (3.8)
Septic cholestasis 2 (3.8)
Recurrent pyogenic cholangitis 1 (1.9)

*CMV, cytomegalovirus; HBV, hepatitis B virus; HCV, hepatitis C virus; HEV, hepatitis E virus.
†All results are no. (%) unless otherwise indicated.
‡All percentages based on no. patients with biochemical hepatitis.

Main Article

Page created: November 20, 2018
Page updated: November 20, 2018
Page reviewed: November 20, 2018
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