Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 24, Number 2—February 2018
Research

Spread of Meropenem-Resistant Streptococcus pneumoniae Serotype 15A-ST63 Clone in Japan, 2012–2014

Satoshi NakanoComments to Author , Takao Fujisawa, Yutaka Ito, Bin Chang, Yasufumi Matsumura, Masaki Yamamoto, Miki Nagao, Shigeru Suga, Makoto Ohnishi, and Satoshi Ichiyama
Author affiliations: Kyoto University Graduate School of Medicine, Kyoto, Japan (S. Nakano, Y. Matsumura, M. Yamamoto, M. Nagao, S. Ichiyama); National Hospital Organization Mie National Hospital, Tsu, Japan (T. Fujisawa, S. Suga); Nagoya City University Graduate School of Medical Science, Nagoya, Japan (Y. Ito); National Institute of Infectious Diseases, Tokyo, Japan (B. Chang, M. Ohnishi)

Main Article

Table 3

PBP 1a, 2b, and 2x transpeptidase conserved amino acid motif profile of Streptococcus pneumonaie isolates from Japan, 2012–2014*

Clone (no.)
Sequences of conserved amino acid motifs of PBPs
pbp1a

pbp2b

pbp2x
SXXK (no.)
SXN (no.)
KTG (no.)
SXXK (no.)
SXN (no.)
KSG (no.)
SXXK (no.)
SXN (no.)
KSG (no.)
MEM-S-15A-ST63 (10) STMK (10) SRN (10) KTG (10) SVVK (10) SSNA (10) KTG (10) SPMK (1), STMK (3), SAMK (6) HSSN (10) VKSG (6), LKSG (4)
MEM-NS-15A-ST63 (24) SSMK (24) SRN (24) KTG (24) SVVK (24) SSNA (24) KTG (24) SAMK (22), SAFK (2) HSSN (24) VKSG (24)
MEM-NS-non15A (32) SSMK (29), SAMK (3) SRN (32) KTG (32) SVVK (32) SSNA (32) KTG (32) SAMK (32) HSSN (32) VKSG (32)
PMEN15A-25 (1) STMK (1) SRN (1) KTG (1) SVVK (1) SSNA (1) KTG (1) STMK (1) HSSN (1) LKSG (1)

*MEM-NS, meropenem-nonsusceptible; MEM-S, meropenem-susceptible; PBP, penicillin binding protein; PMEN, Pneumococcal Molecular Epidemiology Network; ST, sequence type.

Main Article

Page created: January 17, 2018
Page updated: January 17, 2018
Page reviewed: January 17, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external