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Volume 24, Number 2—February 2018

Adenovirus Type 4 Respiratory Infections among Civilian Adults, Northeastern United States, 2011–20151

Adriana E. KajonComments to Author , Daryl M. Lamson, Camden R. Bair, Xiaoyan Lu, Marie L. Landry, Marilyn Menegus2, Dean D. Erdman, and Kirsten St. George
Author affiliations: Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA (A.E. Kajon, C.R. Bair); New York State Department of Health, Albany, New York, USA (D.M. Lamson, K. St. George); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (X. Lu, D.D. Erdman); Yale University School of Medicine, New Haven, Connecticut, USA (M.L. Landry); University of Rochester Medical Center, Rochester, New York, USA (M. Menegus)

Main Article

Table 2

Basic demographics, clinical characteristics, and virology findings of 33 cases of HAdV-4 acute respiratory infection detected by New York State Department of Health surveillance, New York, USA, 2011–2015*

Case ID Specimen collection date Specimen Patient age, y/sex Setting County Diagnosis Genome type†
NY1 2011 Dec NPS, OPS 19/M College 1 Albany ILI 4a1
NY2 2011 Dec NSW 18/M College 2 Tompkins ILI 4a2
NY3 2012 Jan NPS, OPS 29/M Outpatient visit Broome ILI 4a2
NY4 2012 Jan NPS, OPS 21/F College 1 Albany ILI 4a2
NY5 2012 Jan NPS, OPS 21/M College 1 Albany ILI 4a2
NY6 2012 Jan NPS, OPS 22/M College 1 Albany ILI 4a2
NY7 2012 Apr NPS 22/F College 3 Clinton ILI 4a2‡
NY8 2012 Aug NPS/TA 43/F ICU Ontario Pneumonia, acute respiratory distress syndrome 4a1‡
NY9 2012 Sep NPS 98/F Nursing home Dutchess Pneumonia 4a1
NY10 2012 Oct TS 43/M Cancer center New York Fatal outcome 4a2
NY11 2013 Feb NPS 21/M College 4 Tompkins ILI 4a SmaI v‡
NY12 2013 Feb NPS, OPS 20/F College 4 Tompkins ILI 4a SmaI v
NY13 2013 Mar NPS 19/M College 4 Tompkins ILI 4a SmaI v
NY14 2013 Apr NPS, OPS 18/M College 4 Tompkins ILI 4a SmaI v
NY15 2013 Dec NPS 21/F College 4 Tompkins ILI 4a1
NY16 2014 Feb NPS 19/M College 5 Cortland ILI 4a2‡
NY17 2014 Mar NPS 20/F College 6 Nassau ILI 4a2‡
NY18 2014 Mar NPS 18/F College 7 Broome ILI 4a2
NY19 2014 May NPS, OPS 19/F College 4 Tompkins ILI 4a2
NY20 2014 Oct NPS 18/M College 2 Tompkins ILI 4a1‡
NY21 2014 Dec NPS, OPS 25/F College 4 Tompkins ILI 4a1‡
NY22 2014 Dec NPS 18/M College 2 Tompkins ILI 4a1‡
NY23 2015 Jan NPS 13/M Outpatient visit Schenectady ILI 4a1‡
NY24 2015 Feb NPS, OPS 20/M College 4 Tompkins ILI 4a SmaI/XhoI v‡
NY25 2015 Feb NPS, OPS 18/F Outpatient visit Ulster ILI 4p‡
NY26 2015 Oct NPS 21/M College 2 Tompkins ILI 4a1
NY27 2015 Oct NPS 20/M College 2 Tompkins ILI 4a1
NY28 2015 Oct NPS 18/F College 2 Tompkins ILI 4a1
NY29 2015 Oct NPS 20/M College 2 Tompkins ILI 4a1
NY30 2015 Oct NPS 18/F College 2 Tompkins ILI 4a1
NY31 2015 Oct NPS 18/M College 2 Tompkins ILI 4a1
NY32 2015 Oct NPS 19/F College 2 Tompkins ILI 4a1
NY33 2015 Oct NPS 22/M College 2 Tompkins ILI 4a1

*HAdV-4, human adenovirus type 4; ICU, intensive care unit; ID, identification; ILI, influenza-like illness; NPS, nasopharyngeal swab; OPS, oropharyngeal swab; TA, tracheal aspirate; TS, throat swab; v, variant exhibiting unpublished profiles for the specified endonucleases.
†Determined by restriction enzyme analysis of viral genomic DNA performed in vitro, in silico, or both with BamHI, DraI, EcoRI, EcoRV, SmaI, and XhoI and designated according to Li and Waddell (15).
‡Restriction enzyme analysis by in silico digestion.

Main Article

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Main Article

1Preliminary results from this study were presented at the 12th International Adenovirus Meeting, August 16–20, 2016; Barsinghausen, Germany.


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