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Volume 24, Number 3—March 2018

Invasive Infections Caused by Nannizziopsis spp. Molds in Immunocompromised Patients

Céline Nourrisson, Magali Vidal-Roux, Sophie Cayot, Christine Jacomet, Charlotte Bothorel, Albane Ledoux-Pilon, Fanny Anthony-Moumouni, Olivier Lesens1, and Philippe Poirier1Comments to Author 
Author affiliations: Centre Hospitalier Universitaire Clermont-Ferrand, Clermont-Ferrand, France; 1These authors contributed equally to this article.

Main Article


Characteristics of Nannizziopsis sp. infection in humans*

Year (reference) Age, y/sex Country Underlying condition or context Species Localization Positive samples Treatment Outcome
2017 (this study)
HIV, living in Mali
Nannizziopsis sp.
Brain abscess
Cerebral biopsy, CSF
AmpB for 1 mo, then VCZ
Recovery but neurologic sequela after 2 mo
2015 (this study)
Leukemia, recent travel to Senegal
N. obscura
Brain abscess
Blood culture, CSF, ascites fluid
Not treated
(death before diagnosis)
Death before diagnosis
2005 (2)
HIV, travel to Nigeria
N. obscura
Brain abscess
Needle aspiration of brain lesion
Recovery without sequelae after 4 mo
2005 (5)
United States
N. infrequens
Bronchial washing
Not treated,
considered as a contaminant
Recovery after treatment of CMV infection
2000 (3,4)
United States
Travel to Nigeria
N. hominis
Lymph nodes, heart, lungs, spleen, kidneys
3 lymph nodes
ITRA for 2 y
1994 (3)
United States
N. hominis
Right thigh mass
Deep muscle mass on the right thigh, right groin, buttock, and lung
Death after 8 mo
1982 (1) 24/M United States Travel to Africa N. obscura Abscess in right ankle, osteomyelitis 2 biopsies of abscess in tibia AmpB for 4 mo Recovery after 4 mo

*AmpB, amphotericin B; CMV, cytomegalovirus; CSF, cerebrospinal fluid; ITRA, itraconazole; NA, not available; VCZ, voriconazole.

Main Article

Page created: February 16, 2018
Page updated: February 16, 2018
Page reviewed: February 16, 2018
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