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Volume 24, Number 3—March 2018
Research

Characteristics Associated with Negative Interferon-γ Release Assay Results in Culture-Confirmed Tuberculosis Patients, Texas, USA, 2013–2015

Duc T. Nguyen, Larry D. Teeter, Julie Graves, and Edward A. GravissComments to Author 
Author affiliations: Houston Methodist Research Institute, Houston, Texas, USA (D.T. Nguyen, E.A. Graviss); Forensic Research and Analysis, Portland, Oregon, USA (L.D. Teeter); University of Medicine and Health Sciences, New York, New York, USA (J. Graves); University of Texas School of Public Health, Houston (J. Graves)

Main Article

Table 1

Characteristics of 1,487 culture-confirmed TB patients with negative and positive IGRA results, Texas, USA, 2013–2015*

Characteristic Value
Age, y, median (IQR) 47.0 (30.0–61.0)
Age >60 y
402 (27.0)
Sex
M 942 (63.3)
F
545 (36.7)
Race/Ethnicity
Non-Hispanic white 152 (10.2)
Black 275 (18.5)
Hispanic 762 (51.2)
Asian 288 (19.4)
Other
10 (0.7)
Foreign-born 897 (60.3)
Resident of long-term care facility 20 (1.3)
Homeless 100 (6.7)
Excess alcohol user 257 (17.3)
Injection drug user
38 (2.6)
Chest radiograph result
Normal 160 (10.8)
Consistent with TB 1,240 (83.4)
Unknown/Not done
87 (5.9)
TB site
Pulmonary 1,136 (76.4)
Extrapulmonary 196 (13.2)
Both
155 (10.4)
HIV status
Negative 1,279 (86.0)
Positive 90 (6.1)
Unknown
118 (7.9)
MDR 13 (0.9)
Days from diagnosis to treatment, median (IQR) 3.0 (0–13.0)
Died within 1 year of TB diagnosis 105 (7.1)

*Values are no. (%) unless otherwise indicated. Percentages were calculated on the basis of the number of patients with data available. IGRA, interferon-γ release assay; IQR, interquartile range; MDR, multidrug resistance; TB, tuberculosis.

Main Article

Page created: February 15, 2018
Page updated: February 15, 2018
Page reviewed: February 15, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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