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Volume 24, Number 4—April 2018
Dispatch

Emergomyces canadensis, a Dimorphic Fungus Causing Fatal Systemic Human Disease in North America

Ilan S. SchwartzComments to Author , Stephen Sanche, Nathan P. Wiederhold, Thomas F. Patterson, and Lynne Sigler
Author affiliations: Global Health Institute, University of Antwerp, Antwerp, Belgium (I.S. Schwartz); San Antonio Center for Medical Mycology, UT Health San Antonio, San Antonio, Texas, USA (I.S. Schwartz, N.P. Wiederhold, T.F. Patterson); University of Saskatchewan, Saskatoon, Saskatchewan, Canada (S. Sanche); UT Health San Antonio Fungus Testing Laboratory, San Antonio (N.P. Wiederhold); South Texas Veterans Health Care System, San Antonio (T.F. Patterson); University of Alberta Biological Sciences, Edmonton, Alberta, Canada (L. Sigler)

Main Article

Table

Epidemiologic and clinical characteristics of 4 patients infected with Emergomyces canadensis, North America, 1992–2015

Case no.
 Year
 Location
 Patient age, y/sex
 Medical history
 Clinical syndrome
 Specimen cultured
 Treatment
 Outcome
 Strain ID†
1
 1992
 Regina, Saskatchewan
 68/M
 HIV
 Sepsis, skin lesions
 Skin biopsy
 –
 Died
 UAMH 7172 (AF038322)
2
 2003
 Saskatoon, Saskatchewan
 39/M
 Kidney transplant, diabetes
 Pneumonia, tracheitis, lymphadenopathy, esophagitis, sepsis
 Blood, BAL fluid
 Fluconazole, then
amphotericin B
 Survived
 UAMH 10370 (EF592151)
3
 2010
 Colorado Springs, Colorado
 75/F
 –
 Fungemia, endocervical lesion
 Blood
 –
 Died
 UTHSCSA DI17–85 (MG777526, MG777527)
4 2015 Santa Fe, New Mexico 40/M HIV Pneumonia, skin lesions, sepsis Skin biopsy – Survived UTHSCSA DI17–84 (MG777530, MG777528)

*BAL, bronchoalveolar; ID, identification; UAMH, UAMH Centre for Global Microfungal Biodiversity; UTHSCSA, University of Texas Health Science Center at San Antonio; –, data missing.
†GenBank accession numbers for relevant nucleotide sequences are given.

Main Article

Page created: March 19, 2018
Page updated: March 19, 2018
Page reviewed: March 19, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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