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Volume 24, Number 6—June 2018
Dispatch

Intense Focus of Alveolar Echinococcosis, South Kyrgyzstan

Bakhadyr Bebezov, Nurlan Mamashev, Tilek Umetaliev, Iskender Ziadinov, Philip S. Craig, Deborah E. Joekel, Peter Deplazes, Felix Grimm, and Paul R. TorgersonComments to Author 
Author affiliations: Kyrgyz-Russian Slavic University, Bishkek, Kyrgyzstan (B. Bebezov, N. Mamashev, T. Umetaliev); University of Zurich, Zurich, Switzerland (I. Ziadinov, D.E. Joekel, P. Deplazes, F. Grimm, P.R. Torgerson); University of Salford, Greater Manchester, UK (P.S. Craig)

Main Article

Table 2

Ultrasound results partially confirmed with PCR/histology for AE or CE in relation to serology, southern Kyrgyzstan, 2012*

Ultrasound results ELISA
 WB†
No. available samples‡ Neg AE/CE§ AE¶ No. available samples‡ Neg AE/CE CE AE
AE, n = 106 95 55 25 15 43 34 6 3 0
Confirmed AE,# n = 37 33 18 10 5 13 10 3 0 0
Inconclusive, n = 9 6 5 1 0 4 4 0 0 0
CE, n = 3 3 2 1 0 0 0 0 0 0
CE and AE, n = 1
 1
 0
 1
 0
0
 0
 0
 0
 0
Negative but with history of CE/AE, n = 13 6 1 3 2 1 1 0 0 0

*AE/CE indicates the test is specific only to genus level. AE, alveolar echinococcosis; CE, cystic echinococcosis; neg, negative; WB, Western blot. †ELISA-negative serum only.
‡Not every patient for whom echinococcosis was diagnosed by ultrasound had inconclusive results or a history of echinococcosis provided a blood sample. For some of these patients, insufficient serum was available from the blood sample to undertake both ELISA and WB.
§E. granulosus hydatid fluid and/or native protoscolex antigens and/or antigen B positive but Em18 and EmG11 negative.
¶Em18 and/or EmG11 positive (E. granulosus hydatid fluid and/or native protoscolex antigens and/or antigen B positive or negative).
#Diagnosis confirmed by PCR and/or histology of resected lesion.

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Page created: May 17, 2018
Page updated: May 17, 2018
Page reviewed: May 17, 2018
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