Bioclinical Test to Predict Nephropathia Epidemica Severity at Hospital Admission
, Stéphanie Mestrallet, Pascale Halin, Laure-Anne Pannet, Delphine Lebrun, Moustapha Dramé, Firouzé Bani-Sadr, Jean-Marc Galempoix, Christophe Strady, Jean-Marc Reynes, Christian Penalba, and Amélie Servettaz
Author affiliations: University of Reims Champagne-Ardenne, Reims, France (M. Hentzien, M. Dramé); Hôpital Universitaire Robert Debré, Reims (M. Hentzien, M. Dramé, F. Bani-Sadr, A. Servettaz); Manchester Hospital, Charleville-Mézières, France (S. Mestrallet, P. Halin, L.-A. Pannet, D. Lebrun, J.-M. Galempoix, C. Penalba); Groupe Courlancy, Reims (C. Strady); Institut Pasteur, Lyon, France (J.-M. Reynes)
Figure 3. Receiver operating characteristic curve of test to predict development of severe nephropathia epidemica among patients hospitalized for nephropathia epidemica, Ardennes Department, January 2000–December 2014. Severe nephropathia epidemica was defined as the occurrence of >1 of the following criteria: hypovolemic, hemorrhagic, or septic shock; plasma creatinine level >353.6 µmol/L; anuria (urine output <300 mL/d); acute kidney injury or hydroelectrolytic disorders requiring dialysis; hemorrhage requiring blood transfusion; admission to the intensive care unit; or death. Area under the curve is 0.80.
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