TY - JOUR AU - Demetria, Catalino AU - Smith, Ina AU - Tan, Titus AU - Villarico, Daniel AU - Simon, Edson Michael AU - Centeno, Rex AU - Tachedjian, Mary AU - Taniguchi, Satoshi AU - Shimojima, Masayuki AU - Miranda, Noel Lee AU - Miranda, Mary Elizabeth AU - Rondina, Melissa Marie AU - Capistrano, Rowena AU - Tandoc, Amado AU - Marsh, Glenn AU - Eagles, Debbie AU - Cruz, Ramses AU - Fukushi, Shuetsu T1 - Reemergence of Reston ebolavirus in Cynomolgus Monkeys, the Philippines, 2015 T2 - Emerging Infectious Disease journal PY - 2018 VL - 24 IS - 7 SP - 1285 SN - 1080-6059 AB - In August 2015, a nonhuman primate facility south of Manila, the Philippines, noted unusual deaths of 6 cynomolgus monkeys (Macaca fascicularis), characterized by generalized rashes, inappetence, or sudden death. We identified Reston ebolavirus (RESTV) infection in monkeys by using serologic and molecular assays. We isolated viruses in tissues from infected monkeys and determined viral genome sequences. RESTV found in the 2015 outbreak is genetically closer to 1 of the 4 RESTVs that caused the 2008 outbreak among swine. Eight macaques, including 2 also infected with RESTV, tested positive for measles. Concurrently, the measles virus was circulating throughout the Philippines, indicating that the infection of the macaques may be a reverse zoonosis. Improved biosecurity measures will minimize the public health risk, as well as limit the introduction of disease and vectors. KW - Reston Ebolavirus KW - non-human primates KW - measles virus KW - coinfection KW - macaques KW - viruses KW - nonhuman primates KW - zoonoses KW - the Philippines DO - 10.3201/eid2407.171234 UR - https://wwwnc.cdc.gov/eid/article/24/7/17-1234_article ER - End of Reference