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Volume 24, Number 7—July 2018
CME ACTIVITY - Research

Epidemiology and Geographic Distribution of Blastomycosis, Histoplasmosis, and Coccidioidomycosis, Ontario, Canada, 1990–2015

Elizabeth M. Brown1, Lisa R. McTaggart1, Deirdre Dunn, Elizabeth Pszczolko, Kar George Tsui, Shaun K. Morris, Derek Stephens, Julianne V. Kus2Comments to Author , and Susan E. Richardson2
Author affiliations: Public Health Ontario, Toronto, Ontario, Canada (E.M. Brown, L.R. McTaggart, D. Dunn, E. Pszczolko, K.G. Tsui, J.V. Kus, S.E. Richardson); University of Toronto, Toronto (E.M. Brown, S.K. Morris, J.V. Kus, S.E. Richardson); The Hospital for Sick Children, Toronto (S.K. Morris, D. Stephens, S.E. Richardson)

Main Article

Table 2

Temporal and geographic trends of annual incidence and incidence rate ratios of blastomycosis in Ontario, Canada, 1990–2015, by province and region*

Geographic region Years Annual incidence Poisson regression analysis, IRR (95% CI)†
Ontario
1995–1999
 2000–2004
 2005–2009
Ontario 1995–1999 0.19
2000–2004 0.42 3.62 (1.91–6.86)
2005–2009 0.52 4.46 (2.39–8.35) 1.23 (0.82–1.84)
2010–2015
 0.47
 3.87 (2.05–7.31)
 1.07 (0.71–1.62)
 0.87 (0.58–1.29)
Northwest
1995–1999
 2000–2004
 2005–2009
Northwest 1995–1999 1.91
2000–2004 14.60 7.31 (2.87–18.64)
2005–2009 15.49 7.91 (3.11–20.10) 1.07 (0.68–1.69)
2010–2015
 11.90
 6.12 (2.37–15.82)
 0.83 (0.51–1.35)
 0.77 (0.48–1.25)
Southwest
 South-central
 Southeast
 Northeast
Southwest 1995–2015 0.05
South-central 1995–2015 0.29 3.09 (1.01–9.50)
Southeast 1995–2015 0.14 2.00 (0.62–6.49) 0.65 (0.28–1.52)
Northeast 1995–2015 0.87 8.24 (2.82–24.12) 2.66 (1.32–5.35) 4.12 (1.88–9.07)
Northwest 1995–2015 10.9 105.21 (38.78–285.43) 33.97 (19.10–60.41) 52.68 (26.69–104.00) 12.76 (7.92–20.56)

*Incidence is no. cases/100,000 population. IRR, incidence rate ratio.
†IRRs were derived from Poisson regression analysis showing pairwise contrasts of blastomycosis incidence rates between different time intervals and geographic regions. Bold type indicates statistically significant values (p<0.05).

Main Article

1These first authors contributed equally to this article.

2These senior responsible authors contributed equally to this article.

Page created: June 14, 2018
Page updated: June 14, 2018
Page reviewed: June 14, 2018
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