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Volume 25, Number 1—January 2019
Synopsis

Clinical and Radiologic Characteristics of Human Metapneumovirus Infections in Adults, South Korea

Hyun Jung Koo, Han Na Lee, Sang-Ho Choi, Heungsup Sung, Hwa Jung Kim, and Kyung-Hyun DoComments to Author 
Author affiliations: Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea (H.J. Koo, S.H. Choi, H. Sung, H.J. Kim, K.-H. Do); Kyung Hee University Hospitalat Gangdong, Seoul, South Korea (H.N. Lee)

Main Article

Table 4

Clinical characteristics associated with 30-day mortality rate for patients infected with HMPV, South Korea*

Characteristic Recovered, n = 802 30-day mortality rate, n = 47 Univariate analysis
Multivariable analysis
OR (95% CI) p value OR (95% CI) p value
Age
63.5 (53.0–73.0)
67.0 (55.0–77.0)
(0.99–1.04)
0.15

1.02 (1.00–1.05)
0.11
Male sex
416 (52)
26 (55)
0.87 (0.48–1.57)
0.65



Smoking 0.04 0.54
Never 540 (67) 25 (53) 1 1
Former 48 (6) 3 (6) 1.35 (0.39–4.63) 0.63 0.67 (0.15–3.04) 0.61
Current
214 (27)
19 (40)
1.92 (1.04–3.56)
0.04

1.35 (0.69–2.64)
0.39
Body mass index, kg/m2
23.1 (20.5–25.6)
20.5 (18.2–24.1)
0.89 (0.79–0.95)
0.001

0.86 (0.79–0.95)
0.002
Diabetes mellitus 277 (35) 19 (40) 1.29 (0.71–2.35) 0.41 1.48 (0.77–0.95) 0.24
Community-acquired pneumonia 715 (89) 40 (85) 0.70 (0.30–1.60) 0.39 0.83 (0.32–2.11) 0.69
Other pathogen
193 (24)
10 (21)
0.86 (0.42–1.76)
0.68

0.75 (0.35–1.60)
0.45
Underlying condition 0.02 0.02
Immunocompetent 443 (55) 16 (34) 1
Solid tumor 157 (20) 17 (36) 3.00 (1.48–6.08) 0.002 3.43 (1.58–7.44) 0.002
SOT 59 (7) 0 0.00 (0.00–0.00) 1.00 0.00 (0.00–0.00) 1.00
HCT 7 (0.9) 2 (4) 7.91 (1.52–41.1) 0.01 9.19 (1.47–57.37) 0.02
HM 53 (7) 5 (11) 2.61 (0.92–7.42) 0.07 3.44 (1.14–10.34) 0.03
Steroid use 83 (10) 7 (15) 2.34 (0.93–5.85) 0.07 2.40 (0.91–6.34) 0.08

*Values are no. (%) or median (interquartile range). HCT, hematologic stem cell transplantation; HM, hematologic malignancy; OR, odds ratio; SOT, solid organ transplants.

Main Article

Page created: December 18, 2018
Page updated: December 18, 2018
Page reviewed: December 18, 2018
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